CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025451
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Epb4.1l2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
196EVQTSELKAEVASQKubiquitination[1]
263FQDHPEQKNWLDPAKubiquitination[1]
367HTKELEEKVSELHKTubiquitination[1]
392SQFLENAKRLSMYGVubiquitination[1]
405GVDLHHAKDSEGVDIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 988 AA 
Protein Sequence
MTTEVGSASE VKKGSDQAGA DASKEKAKEV ENEQTPVSEP EEEKGSQPGP PVERQSTPRL 60
RKRGKDPSEN RGISRFIPPW LKKQRSYNLV VAKDGGDKKE PTQADVEDQI LGKEESLPEE 120
ESRAKGDAEE MAQRKHLEVQ VEVREAKPAL KSSVETQPAE EVRKDKEETI QDTQEEKLEG 180
GAAKRETKEV QTSELKAEVA SQKATKKTKT VLAKVTLLDG TEYSCDLEKR AKGQVLFDRV 240
CEHLNLLEKD YFGLLFQDHP EQKNWLDPAK EIKRQLKNLP WLFTFNVKFY PPDPSQLTED 300
ITRYFLCLQL RQDIASGRLP CSFVTHALLG SYTLQAEHGD YDPEEYDSID LGDFQFAPAH 360
TKELEEKVSE LHKTHRGLSP AQADSQFLEN AKRLSMYGVD LHHAKDSEGV DIKLGVCANG 420
LLIYKDRLRI NRFAWPKILK ISYKRSNFYI KVRPAELEQF ESTIGFKLPN HRAAKRLWKV 480
CVEHHTFYRL VSPEQPPKTK FLTLGSKFRY SGRTQAQTRE ASTLIDRPAP QFERASSKRV 540
SRSLDGAPIG VVDQSPPGEG SVPGPGVISY TTIQDGRRDS KSPTKATPLP AEGKKNTLRV 600
DGDNIYVRHN NLMLEDLDKA QEAILKHQAS ISELKRNFMT STPEPRPSEW EKRRVTPLPF 660
QPQASSHETL NVVEEKKRAE VGKDESVITE EMNGKEMSPG HGPGETRKVE PVAHKDSTSL 720
SSESSSSSSE SEEDVGEYQP HHRVTEGTIR EEQEECDEEL EEEPGQGAKV VEREAAVPDA 780
VPDRQAGASV LPVETEAQEH VVAQKLPGEK GAHGGTAEQD PREEAEEDPH RVNGEVPHLD 840
LDGLPEIICC SEPPVVKTEM VTISDASQRT EISTKEVPIV QTETKTITYE SPQIDGGAGG 900
DSGVLLTAQT ITSESASTTT TTHITKTVKG GISETRIEKR IVITGDAALD HDQALAQAIR 960
EAREQHPDMS VTRVVVHKET ELAEEGEE 988 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; ISS:MGI.
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0019898; C:extrinsic to membrane; IEA:InterPro.
 GO:0003779; F:actin binding; ISS:MGI.
 GO:0042731; F:PH domain binding; IDA:MGI.
 GO:0030507; F:spectrin binding; IDA:MGI.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0030036; P:actin cytoskeleton organization; ISS:MGI.
 GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
 GO:0008360; P:regulation of cell shape; ISS:MGI. 
Interpro
 IPR008379; Band_4.1_C.
 IPR019749; Band_41_domain.
 IPR019750; Band_41_fam.
 IPR021187; Band_41_protein.
 IPR000798; Ez/rad/moesin_like.
 IPR014847; FERM-adjacent.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR019747; FERM_CS.
 IPR000299; FERM_domain.
 IPR018979; FERM_N.
 IPR018980; FERM_PH-like_C.
 IPR011993; PH_like_dom.
 IPR007477; SAB_dom. 
Pfam
 PF05902; 4_1_CTD
 PF08736; FA
 PF09380; FERM_C
 PF00373; FERM_M
 PF09379; FERM_N
 PF04382; SAB 
SMART
 SM00295; B41 
PROSITE
 PS00660; FERM_1
 PS00661; FERM_2
 PS50057; FERM_3 
PRINTS
 PR00935; BAND41.
 PR00661; ERMFAMILY.