CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011345
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-rich repeat-containing protein 63 
Protein Synonyms/Alias
  
Gene Name
 LRRC63 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
123ASTRIFGKQTNKMESacetylation[1]
127IFGKQTNKMESSRKFacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 REPEAT 323 343 LRR 1.
 REPEAT 344 367 LRR 2.
 REPEAT 368 390 LRR 3.
 REPEAT 392 413 LRR 4.
 REPEAT 414 436 LRR 5.
 REPEAT 437 459 LRR 6.
 REPEAT 460 486 LRR 7.
 REPEAT 487 510 LRR 8.  
Keyword
 Complete proteome; Leucine-rich repeat; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 580 AA 
Protein Sequence
MQKPPLLLRR PLPPKFTKLS LHEKKTHTAK TGKIESLHVA FTEDETTSIK MDRTRFPDVL 60
RNQSLTPINI QNIFLDHCVQ ERVTAISSPQ KSTKHVREQI PDTATGSIFF PHCNSASTRI 120
FGKQTNKMES SRKFKTMKDV YTEKRLENIL ILSSKFSKPK STPGSVIAQK LEKMHPKHQP 180
LPESPGYTYQ HISRDLSATV PSPPPMTVSM KPEGQWPEHF KSTATLTLRV TEFPGFVSLP 240
TPVLPRKPHR QSVIETLVTE NGNIESVPKQ IPPRPPEGLT KTEKIESEIH VVRGEGFKTV 300
AATRYETITA MTNLAIVNCQ VYGRNALNLK GFFILNCPDL TPLAFQLIYL NLSFNDLHYF 360
PTEILCLKNL QILKLRNNPI KEIPSEIQQL EFLRIFTIAF NLITVLPIGL FSLSYLEELD 420
VSYNELTFIP NEIQKLRSLE KLTVDGNELS FFPHGILKLN LTKIQFENNF THPCFWRDNY 480
LNNPQQLTQI ISLFIVQNKL HKFYDKIPVE VQKLLKWGAQ FLTELAPLSI YSSRKAITEG 540
YIAVELPKFE ESKNITEGLL TQKRYEEVMV KCINATTVTS 580 
Gene Ontology
  
Interpro
 IPR001611; Leu-rich_rpt. 
Pfam
 PF00560; LRR_1 
SMART
  
PROSITE
 PS51450; LRR 
PRINTS