CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041883
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Extracellular sulfatase Sulf-2 
Protein Synonyms/Alias
 Sulfatase 2, isoform CRA_b 
Gene Name
 SULF2 
Gene Synonyms/Alias
 hCG_44067 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
694KGLQEKDKVWLLREQubiquitination[1]
834RNMDLGLKDGGSYEQubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 852 AA 
Protein Sequence
MGPPSLVLCL LSATVFSLLG GSSAFLSHHR LKGRFQRDRR NIRPNIILVL TDDQDVELGS 60
MQVMNKTRRI MEQGGAHFIN AFVTTPMCCP SRSSILTGKY VHNHNTYTNN ENCSSPSWQA 120
QHESRTFAVY LNSTGYRTAF FGKYLNEYNG SYVPPGWKEW VGLLKNSRFY NYTLCRNGVK 180
EKHGSDYSKD YLTDLITNDS VSFFRTSKKM YPHRPVLMVI SHAAPHGPED SAPQYSRLFP 240
NASQHITPSY NYAPNPDKHW IMRYTGPMKP IHMEFTNMLQ RKRLQTLMSV DDSMETIYNM 300
LVETGELDNT YIVYTADHGY HIGQFGLVKG KSMPYEFDIR VPFYVRGPNV EAGCLNPHIV 360
LNIDLAPTIL DIAGLDIPAD MDGKSILKLL DTERPVNRFH LKKKMRVWRD SFLVERGKLL 420
HKRDNDKVDA QEENFLPKYQ RVKDLCQRAE YQTACEQLGQ KWQCVEDATG KLKLHKCKGP 480
MRLGGSRALS NLVPKYYGQG SEACTCDSGD YKLSLAGRRK KLFKKKYKAS YVRSRSIRSV 540
AIEVDGRVYH VGLGDAAQPR NLTKRHWPGA PEDQDDKDGG DFSGTGGLPD YSAANPIKVT 600
HRCYILENDT VQCDLDLYKS LQAWKDHKLH IDHEIETLQN KIKNLREVRG HLKKKRPEEC 660
DCHKISYHTQ HKGRLKHRGS SLHPFRKGLQ EKDKVWLLRE QKRKKKLRKL LKRLQNNDTC 720
SMPGLTCFTH DNQHWQTAPF WTLGPFCACT SANNNTYWCM RTINETHNFL FCEFATGFLE 780
YFDLNTDPYQ LMNAVNTLDR DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE 840
QYRGQLWEGW EG 852 
Gene Ontology
 GO:0009986; C:cell surface; IEA:InterPro.
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0005794; C:Golgi apparatus; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro. 
Interpro
 IPR017849; Alkaline_Pase-like_a/b/a.
 IPR017850; Alkaline_phosphatase_core.
 IPR014615; Extracellular_sulfatase.
 IPR024609; Extracellular_sulfatase_C.
 IPR000917; Sulfatase.
 IPR024607; Sulfatase_CS. 
Pfam
 PF12548; DUF3740
 PF00884; Sulfatase 
SMART
  
PROSITE
 PS00523; SULFATASE_1 
PRINTS