| Tag | Content |
|---|
| CPLM ID | CPLM-015245 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protocadherin beta-14 |
Protein Synonyms/Alias | PCDH-beta-14 |
Gene Name | Pcdhb14 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 768 | TNEFKFLKPVLPNFL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
Sequence Annotation | DOMAIN 35 133 Cadherin 1.
DOMAIN 138 242 Cadherin 2.
DOMAIN 247 347 Cadherin 3.
DOMAIN 352 451 Cadherin 4.
DOMAIN 456 561 Cadherin 5.
DOMAIN 568 671 Cadherin 6.
CARBOHYD 169 169 N-linked (GlcNAc...) (Potential).
CARBOHYD 184 184 N-linked (GlcNAc...) (Potential).
CARBOHYD 418 418 N-linked (GlcNAc...) (Potential).
CARBOHYD 567 567 N-linked (GlcNAc...) (Potential).
DISULFID 96 102 |
Keyword | 3D-structure; Calcium; Cell adhesion; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 796 AA |
Protein Sequence | METSLHKAPQ KRQVTAIIFL LLLWEAGSAT ITYSVLEETD RGSLVGNLAK DLGLSLRELI 60
TRGAQILSKG NKQLLQLEQK SGNLLLKEKL DREELCGSTN PCILHFQVLL KSPVQFIQGE 120
IQLQDVNDHA PEFMEDEILL KILESSLPGA VFPLKIAQDL DVGSNTVQNY TISTNAHFHL 180
LTRNHSDGRK YPELVLDKAL DREEQAQIRL TLTAMDSGSP PKTGTTQVVI VVLDINDNAP 240
EFAQGLYEVQ VQENSPVGSL VLTVSARDLD AGTHGELSYS LFQSSNQVLQ AFEVNTDTGE 300
IRVRKLLDFE EIQSYRMEIE ASDGGGLSGK CTVVIHVMDV NDNAPELTMS VLISEIPENS 360
PETIVAIFGI SDPDSGDNGK MVCSVQDRLP FLLKPNEENF YTLVTERALD RESRAEYNIT 420
ITVSDMGTPR LTTQHTITVQ VSDINDNAPA FTHTSYTMFV RENNSPALHI GTISATDSDS 480
GSNAHITYSL LPPHDPQLAL NSLISINADN GQLFALRALD YEALQAFEFH VGATDGGSPA 540
LSSQALVRVV VLDDNDNAPF VLYPMQNASA PCTELLPRAA EPGYLVTKVV AVDRDSGQNA 600
WLSFQLLKTT EPGLFSVWAH NGEVRTTRLL SERDVPKHRL LLLVKDNGEP PHSASVTLHV 660
LLVDGFSQPY LPLPEVARDP AQEDVLTLYL VIALASVSSL FLVSVLLFVG VRLCRKAGET 720
SLGGCSVPEG HFPGHLVDVS GTGTLSQSYQ YEVCLTGGTG TNEFKFLKPV LPNFLNEGGY 780
RNTEENSNFR DSLGFS 796 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0007156; P:homophilic cell adhesion; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |