CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027951
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Endonuclease G inhibitor, isoform A 
Protein Synonyms/Alias
 Endonuclease G inhibitor, isoform B; Endonuclease G inhibitor, isoform C; SD16985p 
Gene Name
 EndoGI 
Gene Synonyms/Alias
 BG:DS07473.2; CG4930; Dmel_CG4930 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
13AEDTQSDKMATAEKVacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Endonuclease; Hydrolase; Nuclease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 359 AA 
Protein Sequence
MSKRKAEDTQ SDKMATAEKV AQNDYTIGLV DPVKDYQKLI ETRVQVDEIV DDDVTKENFD 60
RTAAAARDVI WRLLFDEAGT SQSNTEKASQ LLEEYRGDAC FYDPTPYNEW IVKLRDEVLK 120
KELLDFWRDV LVKKQLGPCW SRDSDLFDSD DTPPLEFYAH AGCTAPFAAS LKVRAALEEQ 180
ASLDQDGPAT PTTPGELSAD DAAALSGEFE ATLTKENPLE EYRTLMKRFV LTKIIVPDSV 240
HQASVKKIAA AAREIIWKLL FDGTPSAEDQ NKAAELLQEY KGDAGFYGPD DYNSWIFNLR 300
DEVLTKELLD FWRDKMVKME LGPSCARDSD YYDNEDPLPF EFYEKAGCKA PFEGPVNDD 359 
Gene Ontology
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
 GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
 GO:0008428; F:ribonuclease inhibitor activity; IDA:FlyBase.
 GO:0008045; P:motor neuron axon guidance; IMP:FlyBase.
 GO:0060702; P:negative regulation of endoribonuclease activity; IDA:FlyBase.
 GO:0045747; P:positive regulation of Notch signaling pathway; IMP:FlyBase. 
Interpro
 IPR014893; Ku_PK_bind. 
Pfam
 PF08785; Ku_PK_bind 
SMART
  
PROSITE
  
PRINTS