CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017526
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 565 
Protein Synonyms/Alias
  
Gene Name
 ZNF565 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
426YECKECGKAFIRVSQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 6 77 KRAB.
 ZN_FING 167 189 C2H2-type 1.
 ZN_FING 195 217 C2H2-type 2.
 ZN_FING 223 245 C2H2-type 3.
 ZN_FING 251 273 C2H2-type 4.
 ZN_FING 279 301 C2H2-type 5.
 ZN_FING 307 329 C2H2-type 6.
 ZN_FING 335 357 C2H2-type 7.
 ZN_FING 363 385 C2H2-type 8.
 ZN_FING 391 413 C2H2-type 9.
 ZN_FING 419 441 C2H2-type 10.
 ZN_FING 447 469 C2H2-type 11.
 ZN_FING 475 497 C2H2-type 12.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 499 AA 
Protein Sequence
MAQGLVTFRD VAIEFSLEEW KCLEPAQRDL YREVTLENFG HLASLGLSIS KPDVVSLLEQ 60
GKEPWMIAND VTGPWCPDLE SRCEKFLQKD IFEIGAFNWE IMESLKCSDL EGSDFRADWE 120
CEGQFERQVN EECYFKQVNV TYGHMPVFQH HTSHTVRQSR ETGEKLMECH ECGKAFSRGS 180
HLIQHQKIHT GEKPFGCKEC GKAFSRASHL VQHQRIHTGE KPYDCKDCGK AFGRTSELIL 240
HQRLHTGVKP YECKECGKTF RQHSQLILHQ RTHTGEKPYV CKDCGKAFIR GSQLTVHRRI 300
HTGARPYECK ECGKAFRQHS QLTVHQRIHT GEKPYECKEC GKGFIHSSEV TRHQRIHSGE 360
KPYECKECGK AFRQHAQLTR HQRVHTGDRP YECKDCGKAF SRSSYLIQHQ RIHTGDKPYE 420
CKECGKAFIR VSQLTHHQRI HTCEKPYECR ECGMAFIRSS QLTEHQRIHP GIKPYECREC 480
GQAFILGSQL IEHYRIHTG 499 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS