UniProt Accession

 OVOL2_MOUSE; Q8CIV7; Q505Q7; Q6F661; Q8CIV6; Q8K0D6; Q9D949 

Genbank Protein ID

 AY090537; AY090538; AB101294; AB101295; AB101296; AB101299; AB101299; AB101299; AK007360; AL808123; CH466519; BC031771; BC057210; BC094445 

Genbank Nucleotide ID

 AAM11991.1; AAM11992.1; BAD29939.1; BAD29940.1; BAD29941.1; BAD29942.1; BAD29943.1; BAD29944.1; BAB24985.1; CAM26789.1; EDL28455.1; AAH31771.1; AAH57210.1; AAH94445.1 

Protein Name

 Transcription factor Ovo-like 2 

Protein Synonyms/Alias

 mOvo2; Zinc finger OVO2; Zinc finger protein 339; Zinc finger protein mOVO 

Gene Name

 Ovol2 

Gene Synonyms/Alias

 Ovo2; Zfp339; Znf339 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
3	*****MPKVFLVKRR	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription regulator. 

Sequence Annotation

 ZN_FING 118 140 C2H2-type 1.
 ZN_FING 146 168 C2H2-type 2.
 ZN_FING 174 197 C2H2-type 3.
 ZN_FING 213 236 C2H2-type 4.
 MOD_RES 268 268 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 274 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
 GO:0044212; F:transcription regulatory region DNA binding; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0001525; P:angiogenesis; IMP:MGI.
 GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.
 GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.
 GO:0060214; P:endocardium formation; IMP:MGI.
 GO:0001947; P:heart looping; IMP:MGI.
 GO:0060347; P:heart trabecula formation; IMP:MGI.
 GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.
 GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.
 GO:0045617; P:negative regulation of keratinocyte differentiation; IEA:Compara.
 GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Compara.
 GO:0010944; P:negative regulation of transcription by competitive promoter binding; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0001755; P:neural crest cell migration; IMP:MGI.
 GO:0001842; P:neural fold formation; IMP:MGI.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0051726; P:regulation of cell cycle; IEA:Compara.
 GO:0010837; P:regulation of keratinocyte proliferation; IMP:BHF-UCL. 

Interpro

 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 

Pfam

 PF00096; zf-C2H2 

SMART

 SM00355; ZnF_C2H2 

PROSITE

 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 

PRINTS