CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013407
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP synthase subunit alpha 
Protein Synonyms/Alias
 ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha 
Gene Name
 atpA 
Gene Synonyms/Alias
 MPN_600; MP242 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
4****MADKLNEYVALacetylation[1]
13NEYVALIKNEIKKYSacetylation[1]
122VDGRGPIKAEEFDQVacetylation[1]
455IPLDYIAKFKQRIMEacetylation[1]
466RIMEEFDKEHPIYKEacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity). 
Sequence Annotation
 NP_BIND 169 176 ATP (Potential).  
Keyword
 ATP synthesis; ATP-binding; Cell membrane; CF(1); Complete proteome; Hydrogen ion transport; Hydrolase; Ion transport; Membrane; Nucleotide-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 518 AA 
Protein Sequence
MADKLNEYVA LIKNEIKKYS KQIFNSEIGK VISVADGIAK VSGLENALLN ELIEFENNVQ 60
GIALNLEQNT VGVALFGDYS KIREGSTAKR THNVMQTPVG DVMLGRIVNA LGEPVDGRGP 120
IKAEEFDQVE KIAPGVMTRK TVNQPLETGI LTIDALFPIG KGQRELIVGD RQTGKTSIAI 180
DTIINQRGKD VYCVYVAMGQ KNSSVAQIVH QLEVTDSMKY TTVVCATASD PASMIYLTPF 240
TGITIAEYWL KQGKDVLIVF DDLSKHAIAY RTLSLLLRRP PGREAFPGDV FYLHSRLLER 300
ACRLNEEHGG GSITALPIIE TQAGDISAYI PTNVISITDG QLFMVSNLFN SGQRPAIHVG 360
LSVSRVGSAA QIKAIKQQTG SLKLELAQYS ELDSFSQFGS DLDENTKQIL ERGKRVMEMI 420
KQPNGKPYSQ THEALFLFAI AKSFIKFIPL DYIAKFKQRI MEEFDKEHPI YKEIATQKSF 480
SEALEAQTNT AFKALVKRFV SALPDYDITK YGTMEELE 518 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:HAMAP.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0042777; P:plasma membrane ATP synthesis coupled proton transport; IEA:HAMAP. 
Interpro
 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR005294; ATPase_F1-cplx_asu.
 IPR023366; ATPase_F1/A1-cplx_a_su_N.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 
SMART
  
PROSITE
 PS00152; ATPASE_ALPHA_BETA 
PRINTS