UniProt Accession

 NUDG_ECOLI; P77788 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74829.1; BAA15549.1 

Protein Name

 CTP pyrophosphohydrolase 

Protein Synonyms/Alias

  

Gene Name

 nudG 

Gene Synonyms/Alias

 ynjG; b1759; JW1748 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
38	LWEFAGGKVEPDESQ	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order. 

Sequence Annotation

 DOMAIN 2 127 Nudix hydrolase.
 MOTIF 37 58 Nudix box.  

Keyword

 3D-structure; Complete proteome; Hydrolase; Magnesium; Manganese; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 135 AA 

Protein Sequence

Gene Ontology

 GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:EcoCyc.
 GO:0006281; P:DNA repair; IDA:EcoCyc. 

Interpro

 IPR020476; Nudix_hydrolase.
 IPR020084; NUDIX_hydrolase_CS.
 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like. 

Pfam

 PF00293; NUDIX 

SMART

  

PROSITE

 PS51462; NUDIX
 PS00893; NUDIX_BOX 

PRINTS

 PR00502; NUDIXFAMILY.