UniProt Accession

 MLRS_RAT; P04466 

Genbank Protein ID

 X00975; J00754 

Genbank Nucleotide ID

 CAA25480.1; AAA41660.1 

Protein Name

 Myosin regulatory light chain 2, skeletal muscle isoform 

Protein Synonyms/Alias

 DTNB; Fast skeletal myosin light chain 2; G2; MLC-2 

Gene Name

 Mylpf 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
47	NRDGIIDKEDLRDTF	acetylation	[1]
63	AMGRLNVKNEELDAM	acetylation	[1]
92	TMFGEKLKGADPEDV	acetylation	[1]
105	DVITGAFKVLDPEGK	acetylation	[1]
112	KVLDPEGKGTIKKQF	acetylation	[1]
166	VITHGDAKDQE****	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 DOMAIN 25 60 EF-hand 1.
 DOMAIN 95 130 EF-hand 2.
 DOMAIN 131 166 EF-hand 3.
 MOD_RES 2 2 N,N,N-trimethylalanine (By similarity).
 MOD_RES 16 16 Phosphoserine (By similarity).  

Keyword

 Calcium; Complete proteome; Metal-binding; Methylation; Motor protein; Muscle protein; Myosin; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 169 AA 

Protein Sequence

Gene Ontology

 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008307; F:structural constituent of muscle; IEA:Compara.
 GO:0006955; P:immune response; IEP:RGD.
 GO:0006936; P:muscle contraction; TAS:RGD.
 GO:0007519; P:skeletal muscle tissue development; IEP:RGD. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 

Pfam

 PF13405; EF_hand_4 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS