| Tag | Content |
|---|
| CPLM ID | CPLM-015965 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | General receptor for phosphoinositides 1-associated scaffold protein |
Protein Synonyms/Alias | GRP1-associated scaffold protein |
Gene Name | GRASP |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 12 | RLRKLQQKEEAAATP | ubiquitination | [1] |
|
Reference | [1] Integrated proteomic analysis of post-translational modifications by serial enrichment. Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA. Nat Methods. 2013 Jul;10(7):634-7. [ PMID: 23749302] |
Functional Description | Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses (By similarity). |
Sequence Annotation | DOMAIN 101 190 PDZ.
REGION 181 258 Interaction with PSCD3 (By similarity).
MOD_RES 94 94 Phosphoserine (By similarity).
MOD_RES 237 237 Phosphotyrosine. |
Keyword | 3D-structure; Alternative splicing; Cell junction; Cell membrane; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Postsynaptic cell membrane; Reference proteome; Synapse. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 395 AA |
Protein Sequence | MTLRRLRKLQ QKEEAAATPD PAARTPDSEV APAAPVPTPG PPAAAATPGP PADELYAALE 60
DYHPAELYRA LAVSGGTLPR RKGSGFRWKN LSQSPEQQRK VLTLEKEDNQ TFGFEIQTYG 120
LHHREEQRVE MVTFVCRVHE SSPAQLAGLT PGDTIASVNG LNVEGIRHRE IVDIIKASGN 180
VLRLETLYGT SIRKAELEAR LQYLKQTLYE KWGEYRSLMV QEQRLVHGLV VKDPSIYDTL 240
ESVRSCLYGA GLLPGSLPFG PLLAVPGRPR GGARRARGDA DDAVYHTCFF GDSEPPALPP 300
PPPPARAFGP GPAETPAVGP GPGPRAALSR SASVRCAGPG GGGGGGAPGA LWTEAREQAL 360
CGPGLRKTKY RSFRRRLLKF IPGLNRSLEE EESQL 395 |
Gene Ontology | GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. GO:0008104; P:protein localization; IEA:Compara. GO:0007165; P:signal transduction; IEA:Compara. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |