Tag | Content |
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CPLM ID | CPLM-014905 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Geranylgeranyl pyrophosphate synthase |
Protein Synonyms/Alias | GGPP synthase; GGPPSase; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranyltranstransferase |
Gene Name | Ggps1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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25 | YLLQLPGKQVRTKLS | acetylation | [1] | 30 | PGKQVRTKLSQAFNH | acetylation | [1] | 293 | ALVKHLSKMFTEENE | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. |
Sequence Annotation | METAL 64 64 Magnesium 1 (By similarity). METAL 64 64 Magnesium 2 (By similarity). METAL 68 68 Magnesium 1 (By similarity). METAL 68 68 Magnesium 2 (By similarity). METAL 188 188 Magnesium 3 (By similarity). BINDING 25 25 Isopentenyl diphosphate (By similarity). BINDING 28 28 Isopentenyl diphosphate (By similarity). BINDING 57 57 Isopentenyl diphosphate (By similarity). BINDING 73 73 Dimethylallyl diphosphate (By BINDING 74 74 Isopentenyl diphosphate (By similarity). BINDING 151 151 Dimethylallyl diphosphate (By BINDING 152 152 Dimethylallyl diphosphate (By BINDING 185 185 Dimethylallyl diphosphate (By BINDING 202 202 Dimethylallyl diphosphate (By BINDING 212 212 Dimethylallyl diphosphate (By |
Keyword | Complete proteome; Cytoplasm; Isoprene biosynthesis; Magnesium; Metal-binding; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 300 AA |
Protein Sequence | MEKTKEKAER ILLEPYKYLL QLPGKQVRTK LSQAFNHWLK VPEDKLQIII EVTEMLHNAS 60 LLIDDIEDSS KLRRGFPVAH SIYGVPSVIN SANYVYFLGL EKVLTLDHPD AVKLFTRQLL 120 ELHQGQGLDI YWRDTYTCPT EEEYKAMVLQ KTGGLFGLAV GLMQLFSDYK EDLKPLLDTL 180 GLFFQIRDDY ANLHSKEYSE NKSFCEDLTE GKFSFPTIHA IWSRPESTQV QNILRQRTEN 240 IDIKKYCVQY LEDVGSFEYT RYTLRELEAK AYKQIEACGG NPSLVALVKH LSKMFTEENE 300 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004161; F:dimethylallyltranstransferase activity; IEA:EC. GO:0004311; F:farnesyltranstransferase activity; ISS:UniProtKB. GO:0004337; F:geranyltranstransferase activity; IEA:EC. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0045337; P:farnesyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway. GO:0033384; P:geranyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway. GO:0033386; P:geranylgeranyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway. GO:0006720; P:isoprenoid metabolic process; ISS:UniProtKB. |
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PRINTS | |