CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040125
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Vitamin D 25-hydroxylase 
Protein Synonyms/Alias
  
Gene Name
 Cyp2r1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
188FLSRLIEKAAVNRKPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 268 AA 
Protein Sequence
IFSLDLGGIS TVVLNGYDVV KECLVHQSEI FADRPCLPLF MKMTKMGGLL NSRYGRGWID 60
HRRLAVNSFH YFGSGQKSFE SKILEETWSL IDAIETYKGG PFDLKQLITN AVSNITNLIL 120
FGERFTYEDT DFQHMIELFS ENVELAASAP VFLYNAFPWI GILPFGKHQR LFRNADVVYD 180
FLSRLIEKAA VNRKPHLPHH FVDAYLDEMD QGQNDPLSTF SKENLIFSVG ELIIAGTETT 240
TNVLRWAILF MALYPNIQVL ERSRHVLS 268 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
 GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:MGI. 
Interpro
 IPR001128; Cyt_P450.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
  
PRINTS
 PR00463; EP450I.