CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015534
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleoporin NUP188 homolog 
Protein Synonyms/Alias
  
Gene Name
 Nup188 
Gene Synonyms/Alias
 Kiaa0169 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
470KVYSFLDKMSFYNELubiquitination[1]
481YNELHKHKPHDVLSHubiquitination[1]
500LWRRQTPKLLYPLGGubiquitination[1]
876RLAIQLLKRLATVAPubiquitination[1]
1737GKATSLSKASPESQEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May function as a component of the nuclear pore complex (NPC). 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 1719 1719 Phosphoserine (By similarity).
 MOD_RES 1727 1727 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; Direct protein sequencing; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1759 AA 
Protein Sequence
MAAAAGGPCV RSSRELWTIL LGRSALRELN QIEAELNKYW QRLLEGLSYY KPPSPSSAER 60
VKANKDVASP LKELGLRVSK FLGLDEEQSV QLLQCYLQED YRGTRDSLKT VLQDERQSQA 120
LTLKIADYYY EERTCILRCV LHLLTYFQDE RHPYRAEYAD CVDKLEKELV LKYRQQFEEL 180
YRTEAPTWET HGNLMTERQV SRWLVQCLRE QSMLLEIIFL YYAYFEMAPS DLLVLTKMFK 240
EQGFGSRQTS RHLVGGTMDP FVDRIGYFSA LILVEGMDIE SLHKYALDDR RELHQFAQDG 300
LICQDMDRAM LTLGDIPHHA PVLLAWALLR HTLSPEETSS VVRKIGGTAI QLNVFQYLTR 360
LLRSLASGGN DCTTSTACMC VYGLLSFALT SLELHTLGNQ QDVIDTACEV LADPSLPELF 420
WGTEPTSGLG IILDSVCGMF PHLLSPLLQL LRALVSGKST AKKVYSFLDK MSFYNELHKH 480
KPHDVLSHED GTLWRRQTPK LLYPLGGQTN LRIPQGTVGQ VMLDDRAYLV RWEYSYSSWT 540
LFTCEIEMLL HVVSTADVIQ HCQRVKPIID LVHKVISTDL SIADCLLPIT SRIYMLLQRL 600
TTVISPPVNV IASCVNCLTV LAARNPAKVW TDLRHTGFLP FVAHPVSNMT QMISAEGMNA 660
GGYGSLLMNS EQPQGEYGVT IAFLRLVTTL VKGQLGSTQS QGLVPCVMFV LKEMLPSYHK 720
WRYNSHGVRE LIGCLILELI HAILNLCQET ELHSSHTPSL PSLCICSLAY TEAGQTVISI 780
MGIGVDTIDM VMAAQPRSDG PEGQGQGQLL IKTVKLAFSV TNNVIRLKPP SNVVSPLEQA 840
LTQHGAHGNN LIAVLAKYIY HRHDPALPRL AIQLLKRLAT VAPMSVYACL GSDAAAIRDA 900
FLTRLQSKIE DMRIKVMILE FLTVAVETQP GLIELFLNLE VKDGSNGSKE FSLGVWSCLH 960
VVLELIDSQQ QDRYWCPPLL HRAAIAFLHA LWQDRRDSAM LVLRTKPKFW ENLTSPLFGT 1020
LSPPSETSEP SVLETCALIM KIICLEIYYV VKGSLDQSLK DTLKKFSSEK RFAYWSGYVK 1080
SLAVYMADTE GSSCTSLLEY QMLVSAWRIL LIIAASHADV MHLTDMAVRR QLFLDVLDGT 1140
KALLLVAASV NCLRLGSMMC TLLLILLRQW KRELGAVEKI LGPLTEILEG VLQADQQLME 1200
KTKAKVFSAF ITVLQMKELR VGDIPQYSQL VLNVCETLQE EVIALFDQTR HSLASDSAAE 1260
DKDSMETDDC PRPRHKDQRD GVCVLGLHLA KELCEVDEDG DSWLQVTRRL PILPTLLTTL 1320
EVSLRMKQNL HFTEAALHLL LTLARTQQGA TAVAGAGITQ SICLPLLSVY QLSSNGTGQT 1380
PSTSRKSLDA PSWPGVYRLS MSLMERLLKT LRYNFLTEAL DFVGVHQERT LQCLNAVKTV 1440
QSLACLEEAD HTVGFILQLS HFRKEWHFHL PQLMRDVQVN LGYLCQACTS LLHSRKMLQH 1500
YLQNKNGDGL PSAVTPRAQR PSTTTTTTTT TTALATPAGC SSKQPTADTE ASEQRALHTV 1560
QYGLLKILSR TLAALRHFTP DVCQILLDQS LDLAEYNFLF ALSFTTPTFD SEVAPSFGTL 1620
LATVNVALNM LGELDKKKES LTQAVGLSTQ AEGTRTLKSL LMFTMENCFY LLISQAVRYL 1680
RDPAVHPRDK QRMKQELSSE LSTLLSSLSR YFRRGAPSSP AAGVLPSPQG KATSLSKASP 1740
ESQEPLIQLV QAFVRHVQR 1759 
Gene Ontology
 GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
 GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR018864; Nucleoporin_Nup188. 
Pfam
 PF10487; Nup188 
SMART
  
PROSITE
  
PRINTS