UniProt Accession

 CRGB_BOVIN; P02526; A2TJU8 

Genbank Protein ID

 X01036; M16894; EF208024 

Genbank Nucleotide ID

 CAA25518.1; AAA30476.1; ABM97504.1 

Protein Name

 Gamma-crystallin B 

Protein Synonyms/Alias

 Gamma-B-crystallin; Gamma-crystallin II 

Gene Name

 CRYGB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Bos taurus (Bovine) 

NCBI Taxa ID

 9913 

Lysine Modification

Position	Peptide	Type	References
3	*****MGKITFYEDR	glycation	[1]

Reference

 [1] Identification of the glycation site of lens gamma B-crystallin by fast atom bombardment tandem mass spectrometry.
 Smith JB, Hanson SR, Cerny RL, Zhao HR, Abraham EC.
 Anal Biochem. 1996 Dec 1;243(1):186-9. [PMID: 8954545] 

Functional Description

 Crystallins are the dominant structural components of the vertebrate eye lens. 

Sequence Annotation

 DOMAIN 2 40 Beta/gamma crystallin 'Greek key' 1.
 DOMAIN 41 83 Beta/gamma crystallin 'Greek key' 2.
 DOMAIN 89 129 Beta/gamma crystallin 'Greek key' 3.
 DOMAIN 130 172 Beta/gamma crystallin 'Greek key' 4.
 REGION 84 88 Connecting peptide.
 CARBOHYD 3 3 N-linked (Glc) (glycation); in vitro.
 DISULFID 19 23  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Eye lens protein; Glycation; Glycoprotein; Oxidation; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 175 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
 GO:0070309; P:lens fiber cell morphogenesis; IEA:Compara. 

Interpro

 IPR001064; Beta/gamma_crystallin.
 IPR011024; G_crystallin-rel. 

Pfam

 PF00030; Crystall 

SMART

 SM00247; XTALbg 

PROSITE

 PS50915; CRYSTALLIN_BETA_GAMMA 

PRINTS

 PR01367; BGCRYSTALLIN.