CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003832
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome c, testis-specific 
Protein Synonyms/Alias
  
Gene Name
 Cyct 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
56YTDANKNKGVIWTEEacetylation[1]
73MEYLENPKKYIPGTKacetylation[1]
89IFAGIKKKSEREDLIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. 
Sequence Annotation
 METAL 19 19 Iron (heme axial ligand).
 METAL 81 81 Iron (heme axial ligand).
 BINDING 15 15 Heme (covalent).
 BINDING 18 18 Heme (covalent).
 MOD_RES 2 2 N-acetylglycine (By similarity).  
Keyword
 Acetylation; Apoptosis; Complete proteome; Electron transport; Heme; Iron; Metal-binding; Mitochondrion; Phosphoprotein; Reference proteome; Respiratory chain; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 105 AA 
Protein Sequence
MGDAEAGKKI FIQKCAQCHT VEKGGKHKTG PNLWGLFGRK TGQAPGFSYT DANKNKGVIW 60
TEETLMEYLE NPKKYIPGTK MIFAGIKKKS EREDLIQYLK EATSS 105 
Gene Ontology
 GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 
Interpro
 IPR002327; Cyt_c_1A/1B.
 IPR009056; Cyt_c_dom.
 IPR003088; Cyt_c_I. 
Pfam
 PF00034; Cytochrom_C 
SMART
  
PROSITE
 PS51007; CYTC 
PRINTS
 PR00604; CYTCHRMECIAB.