CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040472
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Receptor-interacting serine/threonine-protein kinase 1 
Protein Synonyms/Alias
  
Gene Name
 Ripk1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
248EDVASLKKEYPDQSPubiquitination[1]
553ERDGLKEKVYQMLQKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 597 AA 
Protein Sequence
XSDLLEKTDL DSGGFGKVSL CYHRSHGFVI LKKVYTGPNR AEYNEVLLEE GKMMHRLRHS 60
RVVKLLGIII EEGNYSLVME YMEKGNLMHV LKTQIADLGV ASFKTWSKLT KEKDNKQKEV 120
SSTTKKNNGG TLYYMAPEHL NDINAKPTEK SDVYSFGIVL WAIFAKKEPY ENVICTEQFV 180
ICIKSGNRPN VEEILEYCPR EIISLMERCW QAIPEDRPTF LGIEEEFRPF YLSHFEEYVE 240
EDVASLKKEY PDQSPVLQRM FSLQHDCVPL PPSRSNSEQP GSLHSSQGLQ MGPVEESWFS 300
SSPEYPQDEN DRSVQAKLQE EASYHAFGIF AEKQTKPQPR QNEAYNREEE RKRRVSHDPF 360
AQQRARENIK SAGARGHSDP STTSRGIAVQ QLSWPATQTV WNNGLYNQHG FGTTGTGVWY 420
PPNLSQMYST YKTPVPETNI PGSTPTMPYF SGPVADDLIK YTIFNSSGIQ IGNHNYMDVG 480
LNSQPPNNTC KEESTSRHQA IFDNTTSLTD EHLNPIRENL GRQWKNCARK LGFTESQIDE 540
IDHDYERDGL KEKVYQMLQK WLMREGTKGA TVGKLAQALH QCCRIDLLNH LIRASQS 597 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; ISO:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR025735; RHIM_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom. 
Pfam
 PF00531; Death
 PF07714; Pkinase_Tyr
 PF12721; RHIM 
SMART
 SM00005; DEATH 
PROSITE
 PS50017; DEATH_DOMAIN
 PS50011; PROTEIN_KINASE_DOM 
PRINTS