CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034638
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Gpd1l 
Protein Synonyms/Alias
  
Gene Name
 Gpd1l 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
33SNVKNLQKFSSTVKMacetylation[1]
64NNDHENVKYLPGHKLacetylation[1]
132DEGPDGLKLISDIIRacetylation[1]
291KTIEELEKELLNGQKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; NAD; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 351 AA 
Protein Sequence
MAAAPLKVCI VGSGNWGSAV AKIIGSNVKN LQKFSSTVKM WVFEETVNGR KLTDIINNDH 60
ENVKYLPGHK LPENVVAVPN LGEAVQDADL LVFVIPHQFI HKICDEITGR VPKKAVGITL 120
IKGIDEGPDG LKLISDIIRE KMGIDISVLM GANIASEVAA EKFCETTIGS KVLQNGLLFK 180
ELLQTPNFRI TVVDDADTVE LCGALKNIVA VGAGFCDGLC CGDNTKAAVI RLGLMEMIAF 240
AKIFCKGQVS TATFLESCGV ADLITTCYGG RNRKVAEAFA RTGKTIEELE KELLNGQKLQ 300
GPQTSAEVYR ILKQKGLLDK FPLFTAVYQI CYEGRPVTQM LSCLQSHPEH I 351 
Gene Ontology
 GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+] activity; IEA:InterPro.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0017080; F:sodium channel regulator activity; IEA:Compara.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.
 GO:0006734; P:NADH metabolic process; IEA:Compara.
 GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Compara.
 GO:0090038; P:negative regulation of protein kinase C signaling cascade; IEA:Compara.
 GO:2000010; P:positive regulation of protein localization to cell surface; IEA:Compara.
 GO:0010765; P:positive regulation of sodium ion transport; IEA:Compara.
 GO:0002027; P:regulation of heart rate; IEA:Compara.
 GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IEA:Compara.
 GO:0086005; P:regulation of ventricular cardiac muscle cell action potential; IEA:Compara.
 GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IEA:Compara. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR013328; DH_multihelical.
 IPR006168; G3P_DH_NAD-dep.
 IPR006109; G3P_DH_NAD-dep_C.
 IPR017751; G3P_DH_NAD-dep_euk.
 IPR011128; G3P_DH_NAD-dep_N.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF07479; NAD_Gly3P_dh_C
 PF01210; NAD_Gly3P_dh_N 
SMART
  
PROSITE
  
PRINTS
 PR00077; GPDHDRGNASE.