CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018581
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative deoxyribose-phosphate aldolase 
Protein Synonyms/Alias
 DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase 
Gene Name
 Dera 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
85PIRADLLKALNMDDKubiquitination[1]
92KALNMDDKGITTAAVubiquitination[1]
111ARVCDAVKALKAAGCubiquitination[1]
114CDAVKALKAAGCSIPubiquitination[1]
137PAGQTHLKTRLEEIRubiquitination[1]
223FIKTSTGKETVNATFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity). 
Sequence Annotation
 ACT_SITE 218 218 Schiff-base intermediate with
 ACT_SITE 254 254 By similarity.  
Keyword
 Complete proteome; Lyase; Reference proteome; Schiff base. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MAAHCRGTEL DLSWISKVQV NHAAVLRRAQ QIQARRSVKK EWQAAWLLKA VTFIDLTTLS 60
GDDTFSNVQR LCYKAKYPIR ADLLKALNMD DKGITTAAVC VYPARVCDAV KALKAAGCSI 120
PVASVATGFP AGQTHLKTRL EEIRLAVEDG ATEIDVVINR TLVLTGQWEA LYDEVTQFRK 180
ACGEAHLKTI LATGELGSLT NVYKASLVAM MAGSDFIKTS TGKETVNATF PVAIVMLRAI 240
RDFFWKTGNK VGFKPAGGIR TAKESLAWLS LVKEELGDEW LTPDLFRIGA SSLLSDIERQ 300
IYHHVTGRYA AYHDLPMS 318 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:EC.
 GO:0046121; P:deoxyribonucleoside catabolic process; IEA:Compara.
 GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
 GO:0046386; P:deoxyribose phosphate catabolic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR011343; DeoC.
 IPR002915; DeoC/FbaB/lacD_aldolase. 
Pfam
 PF01791; DeoC 
SMART
  
PROSITE
  
PRINTS