CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027469
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 PF14_0315 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
1810NMKYVSEKYPMNTKMacetylation[1]
1983TTINMKKKHKNSLKNacetylation[1]
1985INMKKKHKNSLKNSKacetylation[1]
1989KKHKNSLKNSKEDDLacetylation[1]
1992KNSLKNSKEDDLNNNacetylation[1]
2240SNNSIFFKTLSKKKKacetylation[1]
3508LNENIDSKKNKVLFEacetylation[1]
3903HFKDNVEKIERKENQacetylation[1]
3918NKENTNNKDISPNNAacetylation[1]
3926DISPNNAKIYNNNNNacetylation[1]
4508RKPKNSLKYNKIRNSacetylation[1]
4511KNSLKYNKIRNSNNNacetylation[1]
5149KKVFFNFKRKKSDNKacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 5757 AA 
Protein Sequence
MDYVHPVDVS KVIHGNESFF TFIDFLRTKK VCNRRNVHIE NSFKKLNNIT FDNGYNKENK 60
ILLSLKEIYK LMVDIQNKNK IYRDIKGNYN SNNNKKKNIH EMKKNYYNNL SSWNNYLLYV 120
LKNDIMENSY NVSYIILIFI LINYQKKIFY IINIYYKDIN CQYKKKKKKE SYQKDYSHNN 180
NYSLHLINNI VLLKNKFSNN EISLTSKNFN YNLKIKKKYI YKKKKKKKKK KRVPKRFWLY 240
IQKLFLYKCY LINKTVNYKC ENNILYNQKI NYLYNIKKKK NFLFKNFILQ KLFWVYKINK 300
HNIQIKQNNN NNNEPFLFTN ILYDSSIKYI CNKLLFIYFC LKNYHHYNDS FDIMRTKHIF 360
MMLWNYIYNT DYYIKSKQVN NSLEYIMNLY IFHNLLKLQV YIIIQISQML IQFILKIITL 420
WIINMMNNII MYLSIIFRMI TILKMFYSTF IINIFVLHKD IILCDQYEKY NDNKQIVHND 480
NYYINRSIIL YNLCNIKQYT IKNYNIINQC IHKLYNIMVI KQKNTYNYIT KSYLCVSFLN 540
QLYYSKTQCI MIYEKNRYSI SLDHLWKSNI NIYFKKILLF LLLLLLLFSS YNNLNNTNVL 600
QLYDCYKYNV HNNYLFIYFN TLIVASILNL LYIFYYVCIN KFCIYLYRDC IISFFLLYIF 660
ILYLYKYYNH IIKIRDISRL SYIIYVVVLL IHIMMYIKCL YNLIRIISLV MFFFVFINTS 720
LSYPNMKINN IIAYYNNTYN SICKFYLLYI PTIFNMYKYS SLLICIYFIH TINVFVNCVT 780
FILLHFIMIL SFSLFMDMYI CSAPILYDTH LSKKKIMNFE KDRRYTFVSY SSSYALMRTI 840
NLIHLNKLYI YDIFIKRNLV GCHGFTLFIH EKHETNDYIV NNNYNIVIVL VLILVGRRNR 900
TIQIEDRRII YKLPVIILNL PSRKNKIYTN IYSCEKHFNT KLYCFFIFKQ RNNNEIVDGV 960
HNEKSKNYYM NDHVKFVKNK KSFLIQTYSD LYHFKNYNDN KIFNNISLCY NINLEHRMNN 1020
VQKYIHADMS IHFKKNYKRD KGINQYIYNY KHNFYLRVFN FLLNFIKRTK NVINIVLCIF 1080
KLLILTKEIL VYYILNLFIY YYIWLKCYFV LYNIIYEYIE RKDYMLMGLY NNSKRFKDND 1140
KKDLFNKNIN EEKERKAKFV SCATNNEYND NNNNNDNNND NNNNNNDNNN DNNNNNDNNN 1200
DNNNDNNNNN YNNNNNNNNN NNNNNNNYNN NNNGGGDRND ENNDKDKKED NDNDNINNML 1260
ENDDGKKKRT RRRKTSDKSK TINKMTTGRR GRKSTSMLNA HIDANNILKN NLYNINNGNY 1320
MNNINNSILL NNNMQENYMN DNKSSNMLMN NIPNKMNMKM NGQINNEIMN DMINYNMNNN 1380
MGNHMNNNMG NHMNNNMGNH MNNHISNHMN NHISNHMNNQ LNNNIYVNNR VGIGYMSNSV 1440
NQHNHMSPHM NNTINVHNNN NNNNNSNNNN NNNNNNNNNN NNNSSSGSNC VNNTLRNNLM 1500
KNNFNQFNRM VNNNSINIHT SSSNINNNMN NYNIHLTHQK INSNNNNINN NNLNMNGKLN 1560
YHQMSNKVHG TVPIPMNVHM GGTSISNINH MNNINNMNNM NNINNMGSSN RMGTSPINHP 1620
IPHKKGGTHM SNQITRNAMN KMLSNPINVD NKMNVLNRKN SCTVNFNMNN PMVSNMNNYM 1680
NSNNMNRNSL PNNICSGGTI MPNVMSKGKI KDTAINNNSF RNNNNINNMN NMNSMNHMNS 1740
MNHMNSMNHM NNVNHMNNMN NVNSMMNNRM SEQNIIANNM IKTEMRNNNL MNMKLVNRNQ 1800
HMNMKYVSEK YPMNTKMIQN NNMVTNRDMN IINNNNINGI NNMGFINYMN KNNTLNKNMK 1860
NIKTENYTYD HHLLNHDPLS PMDTYDIQHM NNNINNMNNI NNVNNINNIN NINSINNINN 1920
MNSIHSVNTK FMLNKQEDDK TLHPNYLNNQ NVQSNTYYHQ TKEEEINTYN NTHSSTTINM 1980
KKKHKNSLKN SKEDDLNNNQ NLRSVKINWN KYDNLFKRIP LERNYEGFIL EQKNIKDEDT 2040
INDEKTFMLE NNEDKEDDAI YCDLSNINFK TFFKDYNDIL NKLNLIKLND KTNFKNNCYS 2100
QLYEEIFLII EKFLDISHLK YHNNFTHTNF YNNCLKYAIY QNKENTNLHN IKEENVDNKN 2160
IHGLDIHLTH ENNETNKEDH NQNDNNENNT KKNNNNNDHN NDDHNNDDHN NNDIKYLIFK 2220
GKSSIFDSVS KSSNNSIFFK TLSKKKKEFN ELCEKNNNFD FVPRNVNLIQ ANESNINMYP 2280
SNASSLTISK NNTLKNSVVR SPSKDVNVET PTTFENNIVN NNNNNNNNDS NNNNNYNNNL 2340
FSSKRSLSES KLIFNQNVLI EEILSKKYRT FSINEFLDVE LNNNLKELVR VYKKNLCYNI 2400
KTFLKKKMKG SKKMYHQKSY YDTLSHLFKH RMTRKLFKRI KRKFLKTTKK RINKMKKKKC 2460
KKNMKNEEIS KQKNGNIVDD SLFLETTDQI DKCDTRNKST VDEKNGMDEY LDEEEKPLFS 2520
FCSGSSRKKK HMDDDRDLIE RGIIRIKGEF SEDSNIIHSN NITSDSTQKG RKNTTSKMNK 2580
FVEGKLNSNI CSKDNNYILY QVKMEEDQMD PLKINNDDNK NDDNNNNDNN NNNNNDCNNN 2640
NNNDCNNNNN NDCNNNNNND CLSLDERKVS NACLESGQQK EFNHINISNN NNNNNNINNN 2700
NNSNNNSNSN ESPFSSNVSS NKTSGNYDIN VYIEKESMKI KYSMTKDKDT TEDKKKNKNK 2760
EDTQINEKLF KYSFLNLSLY RYMKNLENQR NKNTCDKIKK QQKKKQTNVK YKTNAIIDFG 2820
EKIVWVSFEF KNLHMLKKIK NNFLCSNYLN NIQNITKEPE EKFEKYITDE MKKYKNIKIK 2880
FYKFLTYYDF VFLKNRLNFI KITYKNDNDY MLQRAGEETK SAMGINNGST NFQDENKELK 2940
FNDSTDCLLN GYKMDECNNI SNNNNNNILI NKNTNNEMSE MNNVTLKSKV KKESKRLLKR 3000
NKLFNDNISL YPLIDKKKLN SYIDLNLNVD VKKEELENGC EEKLNDKVLS FINKYLYKGL 3060
KIDTKNECSK MGIYENYDKI KNMTIGMDKS NDSIIIDNFL WYNNPALFTI FEKYYLLLKM 3120
QKYILQYKHY SKNNLKKKIS SESNFEMYSS STSINCTSLN KLKGKRRCIR VKTANFGEDG 3180
CLLPKHNRRS NVSNSHRYMN NINEKKKKKG SITKQVTEND DNNNMNKNNY NNNCNADAPS 3240
TGLDINNENA TTLIDESQIA DINNIKSEPI LEKNDKEEKK GNESITQEKN KEHGSMEPNI 3300
NMDINVDINR DINMDKNNSG LVRKLCHADE NVENAENVEN AENAENAENV ENAENAENAE 3360
NAENAENVDE QKKEKGDEGK ANELIVEKKQ KEEAEEEEEE EDGDENSVSS SSTVKQLDNN 3420
LNINGEVSNN IKKELQKGRN TRLGNNKVNT KRYCSSQGTT PRGEMNFLED TDDENLKRKR 3480
GRKKGKKRGR KKGVKNEIKL LNENIDSKKN KVLFEGLIEE SNAKGYNKLG NKILMQDGGE 3540
MLDNSLIGID EKENELLLNE LVPIDKDIII DLLCEEEKLI ESYIKNSRFV DKNLICLLIY 3600
MNNIQKKLSS ICNNLLKKIM KENKMPTRLC DNIEKSNEIT YKYIMFERWN QLRYSLFYTI 3660
SLMNSSIQYN HNHNNNNNNN HHHFHNNDKN NKNNKNNKNQ LLIYNKNINI NSIFDLHEYS 3720
CKHKKYKIPP FEYSVFLKYK IYKKNKTSTK KDDLNENIKD STIKNISDDI NDSIDEKPKE 3780
DIIQNLEDKK NNFANDEEKF CGFSNNNDLN ITPAFSYCCI CFNDDYNTMQ INEQNENHNN 3840
SSRNNSLQNI TNDKKNENLN NKIKSGKQDE QKEQEEKEEK EEKKENIKIK ENNNLHFKDN 3900
VEKIERKENQ NKENTNNKDI SPNNAKIYNN NNNDKNNLYN YCQNKKNSNC SSSSNDVDMK 3960
LIERNIKNTH NLMLKCSRCY MHVHKFCYIS TKKSDENILS NIQNSASINS NEWLCQRCEF 4020
EKKSLGNNFL YIFDTNIKCY ICIERGGAFI QIKNNIFVHT FCATFCVPDL LVNNNVNLEI 4080
FNEYLQLNNM SLSQEIFSAF QKKKKQKINQ KKKQRKDYIS VKDSNIKQLY HNNNNNNTEC 4140
NDAEHVYFKK IKESDKEINE KDDHAHTNDK IHDVLQHDNE CENEKEAHSC KSVFSSNNKN 4200
EEICEQKCEQ KCEQKCKEVM KKKKENKIYD FFSFIKKDDK KRGNECASTV ENIQKRVKLD 4260
NMDEKKNEDY TNDNLNDNKN SNTNNKEKED TNNVMCDNNN NINKMKSPQS CNVKYDINLD 4320
DDHDNESYTS EASSLSVVSR YSINSISTLS DKNNMKLCNK GKEKKDKIKI EDTYNDINKY 4380
IKKDYILNGY LNEDVRCDVC LKNKGIFIKC HNMNCGKYIH PLCAYMCGLF IKCKNSNKKF 4440
LKFQNKIDYC FPRIFFYVKC ILHSIKKYGV VNIYDQIITR RTKYLNRDLY PNIYENNKKE 4500
RKPKNSLKYN KIRNSNNNNN NNNNNNSSSN NYYYFNVNIN KKNDIYEILA YNFNHLDSYQ 4560
YNFFLLPTID YMKNNICLVC FTSYKKSELV HCKYCNMCVH KNCYLVDSSY LEYQFYRKKK 4620
NTCTLLVHNK EHKIVNLISQ MKARKESVLS FLYDQNVGRI NNYTTINNTT NSYINNQSSY 4680
SQVVDSEGLF MSPNYYERKK KKKNHSFGDN IISYSLNENE SNNDKIKINK NGNSFPKEDL 4740
YDNGQINNSC DNFVLNKEDK DIIIDNNNNN NNNNEEIFLK NCKSEKYNCD NDNCHNNNNE 4800
SIINPCVDKN MDANCNIDKL LNKNDSYDNF GKGNDFNSGN NIHGDYMNSK DNLIYHDENV 4860
SFDIDDNNDN NMKYRKELEN SEIFKELIHN EINNCLFTKE NEEKVDFVNK LRDFFRNDKT 4920
YESLKKCTSE EEKCVTDIDD VYEKKLFVCD LCANNYNYEN VNCILCSRKG GALKMVKIND 4980
YIKIDKTKNK KNSFMKNERD YVFVHMQCAL YTPQVVIQDI NEEYYQIYNY DNININNLNE 5040
KELMKKKHYE SDTELQYLNV EYNQDEKQSL LNEFYYKQFC NNIGQMKNIK KGIDKRNSLP 5100
IRNTHKLYDL PEYEQIYPLD NMNNMNNMNN NYNVSSCNNI YKKVFFNFKR KKSDNKEKEE 5160
EEEEVANIKI NDFNNDQGEN KNKTEFNLVN NHEINTDQND NNQVYDNQNN DESKNSNHDH 5220
ILENNQGNDI TNSVALTTVE DICEKGNQTL NNNLEIKKEE SSFSNKVTNE NIKIINVNSY 5280
NKWKSGRFSV YNNICFNNKM KINKRGTIGT TTGISGYHGN HLNVNKFINK KLKKNKEYIS 5340
STYNDNKNNY KNLNNINKKI LYNRRNTNLY YYNLNRKKNN YKIIIKDRIK KYLNKNTCYI 5400
CNLSYGYTQK CVENTCTHYF HISCARIHKL FFEFDYNFLK THPDSTTTDL SKIPNSMIFC 5460
EDHSKIRRRV KPSIKLFSKL RSFLELARII VDQMKKREDI KNSWITDKYK NALYNNDMLY 5520
DEENDITSSA LYNDDNNMEI VNLHNDSNYY NYDDDDDDNN NDDSIDHNNE DYEYEENDPY 5580
CEQKYAYTTS KDHYNNDDDI SLVRNNKRRN RRLLNNVPND HIKNELNINY TNEMSSHNMR 5640
EKSHNLMFPS NSNDKDKISF LVSNEGGAVN NDEHEKENDF INFKTEQESM NENNENNEEN 5700
ENNEENEENE NNENNENNEN NEEIKEKEPN TFYNSVQDDN VKAEDYKDEN NDNDGDI 5757 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001965; Znf_PHD. 
Pfam
  
SMART
 SM00249; PHD 
PROSITE
  
PRINTS