CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026850
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed DNA/RNA polymerase mu 
Protein Synonyms/Alias
 POLM protein; Polymerase (DNA directed), mu, isoform CRA_d 
Gene Name
 POLM 
Gene Synonyms/Alias
 hCG_1745198 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
277QKLTQQQKAAPPGPEubiquitination[1]
415RRFSRKEKGLWLNSHubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 457 AA 
Protein Sequence
MLPKRRRARV GSPSGDAASS TPPSTRFPGV AIYLVEPRMG RSRRAFLTGL ARSKGFRVLD 60
ACSSEATHVV MEETSAEEAV SWQERRMAAA PPGCTPPALL DISWLTESLG AGQPVPVECR 120
HRLEVAGPRK GPLSPAWMPA YACQRPTPLT HHNTGLSEAL EILAEAAGFE GSEGRLLTFC 180
RAASVLKALP SPVTTLSQLQ GLPHFGEHSS RVVQELLEHG VCEEVERVRR SERYQTMKLF 240
TQIFGVGVKT ADRWYREGLR TLDDLREQPQ KLTQQQKAAP PGPEHPSPAV RCRCPAAGGG 300
GSCGAGPAWG HRHADRRLPQ GLILYHQHQH SCCESPTRLA QQSHMDAFER SFCIFRLPQP 360
PGAAVGGSTR PCPSWKAVRV DLVVAPVSQF PFALLGWTGS KLFQRELRRF SRKEKGLWLN 420
SHGLFDPEQK TFFQAASEED IFRHLGLEYL PPEQRNA 457 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR001357; BRCT_dom.
 IPR002054; DNA-dir_DNA_pol_X.
 IPR010996; DNA_pol_b-like_N.
 IPR018944; DNA_pol_lambd_fingers_domain.
 IPR022312; DNA_pol_X.
 IPR027421; DNA_pol_X_lyase_dom.
 IPR001726; TdT/Mu. 
Pfam
 PF10391; DNA_pol_lambd_f 
SMART
 SM00292; BRCT
 SM00483; POLXc 
PROSITE
 PS50172; BRCT 
PRINTS
 PR00869; DNAPOLX.
 PR00871; DNAPOLXTDT.