CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010127
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 
Protein Synonyms/Alias
 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT 
Gene Name
 plsC 
Gene Synonyms/Alias
 MPN_299; MP537 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
182SRQIGEFKSGALKVAacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819
Functional Description
 Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. 
Sequence Annotation
 MOTIF 92 97 HXXXXD motif.  
Keyword
 Acyltransferase; Complete proteome; Lipid biosynthesis; Lipid metabolism; Phospholipid biosynthesis; Phospholipid metabolism; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 266 AA 
Protein Sequence
MKKLTQAFLR FCLRFLQLLS LVLVLPVFVL MLISSLISAK NYESIPENYP PEIRFKKVYR 60
LVSLFLYIKG VKVVIVNPEN VPKKAVLVVA NHKSNLDPLI LIKAFGKTEG VPPLTFIAKI 120
ELQDTWLFKI MKLIDCVFID RKNLRQMAAS LEQQQQIIRQ GTALCVFPEG TRVLSRQIGE 180
FKSGALKVAY NAFVPIVPLT IVGSMGHMES KKRLQKAQVE RDRGYKIQVI FNTPINPINF 240
NQIDSQNVAN NVWREISQTY AQYCQD 266 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:EC.
 GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR004552; AGP_acyltrans.
 IPR002123; Plipid/glycerol_acylTrfase. 
Pfam
 PF01553; Acyltransferase 
SMART
 SM00563; PlsC 
PROSITE
  
PRINTS