CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032165
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GRB2-related adapter protein 2 
Protein Synonyms/Alias
 cDNA FLJ52037, highly similar to GRB2-related adapter protein 2 
Gene Name
 GRAP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40FKVMRDNKGNYFLWTubiquitination[1]
49NYFLWTEKFPSLNKLubiquitination[1]
55EKFPSLNKLVDYYRTubiquitination[1]
69TNSISRQKQIFLRDRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 258 AA 
Protein Sequence
MGKEVGFFII RASQSSPGDF SISVRHEDDV QHFKVMRDNK GNYFLWTEKF PSLNKLVDYY 60
RTNSISRQKQ IFLRDRTRED QGHRGNSLDR RSQGGPHLSG AVGEEIRPSM NRKLSDHPPT 120
LPLQQHQHQP QPPQYAPAPQ QLQQPPQQRY LQHHHFHQER RGGSLDINDG HCGTGLGSEM 180
NAALMHRRHT DPVQLQAAGR VRWARALYDF EALEDDELGF HSGEVVEVLD SSNPSWWTGR 240
LHNKLGLFPA NYVAPMTR 258 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR000980; SH2.
 IPR001452; SH3_domain. 
Pfam
 PF00017; SH2
 PF00018; SH3_1 
SMART
 SM00252; SH2
 SM00326; SH3 
PROSITE
 PS50001; SH2
 PS50002; SH3 
PRINTS
 PR00401; SH2DOMAIN.
 PR00452; SH3DOMAIN.