CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013826
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proteasome maturation protein 
Protein Synonyms/Alias
 Proteassemblin 
Gene Name
 POMP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 
NCBI Taxa ID
 9601 
Lysine Modification
Position
Peptide
Type
References
39RKGFSCVKNELLPSHubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
 Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation (By similarity). Mediates the association of 20S preproteasome with the endoplasmic reticulum (By similarity). 
Sequence Annotation
  
Keyword
 Chaperone; Complete proteome; Cytoplasm; Endoplasmic reticulum; Membrane; Microsome; Nucleus; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 141 AA 
Protein Sequence
MNARGLGSEL KDSIPVTELS ASGPFESHDL LRKGFSCVKN ELLPSHPLEL SEKNFQLNQD 60
KMNFSTLRNI QGLFAPLKLQ MEFKAVQQVQ RLPFLSSSNL SLDVLRGNDE TIGFEDILND 120
PSQSEVMGEP HLMVEYKLGL L 141 
Gene Ontology
 GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0031090; C:organelle membrane; IEA:UniProtKB-SubCell.
 GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
 GO:0043248; P:proteasome assembly; IEA:Compara. 
Interpro
 IPR008012; UMP1. 
Pfam
 PF05348; UMP1 
SMART
  
PROSITE
  
PRINTS