CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033619
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 5'-nucleotidase domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 NT5DC2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
329PFRKLDEKGSLQWDRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 ACT_SITE 110 110 Nucleophile (By similarity).
 ACT_SITE 112 112 Proton donor (By similarity).
 METAL 110 110 Magnesium (By similarity).
 METAL 112 112 Magnesium; via carbonyl oxygen (By
 METAL 370 370 Magnesium (By similarity).  
Keyword
 Complete proteome; Magnesium; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 532 AA 
Protein Sequence
MAGAGLRAAA RRWLLCGGHG GPRAASSSPS CPGCGPPGPG AHCPGVPRSA PAQAPTSGAD 60
LSAHLWARYQ DMRRLVHDLL PPEVCSLLNP AAIYANNEIS LRDVEVYGFD YDYTLAQYAD 120
ALHPEIFSTA RDILIEHYKS LLMKIDAFHY VQLGTAYRGL QPVPDEEVIE LYGGTQHIPL 180
YQMSGFYGKG PSIKQFMDIF SLPEMALLSC VVDYFLGHSL EFDQAHLYKD VTDAIRDVHV 240
KGLMYQWIEQ DMEKYILRGD ETFAVLSRLV AHGKQLFLIT NSPFSFVDKG MRHMVGPDWR 300
QLFDVVIVQA DKPSFFTDRR KPFRKLDEKG SLQWDRITRL EKGKIYRQGN LFDFLRLTEW 360
RGPRVLYFGD HLYSDLADLM LRHGWRTGAI IPELEREIRI INTEQYMHSL TWQQALTGLL 420
ERMQTYQDAE SRQVLAAWMK ERQELRCITK ALFNAQFGSI FRTFHNPTYF SRRLVRFSDL 480
YMASLSCLLN YRVDFTFYPR RTPLQHEAPL WMDQLCTGCM KTPFLGDMAH IR 532 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR023214; HAD-like_dom.
 IPR008380; HAD-SF_hydro_IG_5-nucl.
 IPR016695; Pur_nucleotidase. 
Pfam
 PF05761; 5_nucleotid 
SMART
  
PROSITE
  
PRINTS