CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014130
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SH2 domain-containing adapter protein E 
Protein Synonyms/Alias
  
Gene Name
 SHE 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
118LIQAAAGKGRKNSRAacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 395 490 SH2.  
Keyword
 Complete proteome; Reference proteome; SH2 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 495 AA 
Protein Sequence
MQWSPTPGAS ACLGWASSLA CSTAPTLLGR AGRGPLMAAK WFKEFPLNLK TVSERAKPGG 60
GGGKLRKNSE AGGAGPGPGK GRKNSAAELG SGRAGVGPKD SRLSRDSLQG LIQAAAGKGR 120
KNSRATEEEP HRGATKSSGC STYINRLIKV DTQEKNGKSN YPSSSSSSSS SSSSASSSPS 180
SLGPELDKGK IIKQQETVII LEDYADPYDA KRTKGQRDAE RVGENDGYME PYDAQQMITE 240
IRRRGSKDPL VKALQLLDSP CEPADGGLKS ETLAKRRSSK DLLGKPPQLY DTPYEPAEGG 300
PRAEGKARPP DSRLPENDER PAAEYEQPWE WKKEQIVRAL SVQFEGAERP SFREETVRQH 360
HRQKSWTQKI LKPALSDHSE GEKVDPGLPL EKQPWYHGAI SRAEAESRLQ PCKEAGYLVR 420
NSESGNSRYS IALKTSQGCV HIIVAQTKDN KYTLNQTSAV FDSIPEVVHY YSNEKLPFKG 480
AEHMTLLYPV HSKLH 495 
Gene Ontology
  
Interpro
 IPR000980; SH2. 
Pfam
 PF00017; SH2 
SMART
 SM00252; SH2 
PROSITE
 PS50001; SH2 
PRINTS
 PR00401; SH2DOMAIN.