CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035474
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Sptlc1 
Protein Synonyms/Alias
 Serine palmitoyltransferase, long chain base subunit 1 (Predicted), isoform CRA_a 
Gene Name
 Sptlc1 
Gene Synonyms/Alias
 Sptlc1_predicted; rCG_44191 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
434TQARYLDKEEKCLPPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 473 AA 
Protein Sequence
MATVAEQWVL VEMVQALYEA PAYHLILEGI LILWIIRLVF SKTYKLQERS DLTAKEKEEL 60
IEEWQPEPLV PPVSRNHPAL NYNIVSGPPT HNIVVNGKEC VNFASFNFLG LLANPRVKAA 120
AFASLKKYGV GTCGPRGFYG TFDVHLDLEE RLAKFMKTEE AIIYSYGFST IASAIPAYSK 180
RGDIVFVDSA ACFAIQKGLQ ASRSDIKLFK HNDVADLERL LKEQEIEDQK NPRKARVTRR 240
FIVAEGLYMN TGTICPLPEL VRLKYKYKAR IFLEESLSFG VLGEHGRGVT EHYGISIDDI 300
DLISANMENA LASVGGFCCG RSFVVDHQRL SGQGYCFSAS LPPLLAAAAI EALNIMEENP 360
GIFAVLKKKC QTIHKSLQGV SGLKVVGESL CPALHLQLEE STGSRERDMK LLQEIVEQCM 420
NKGIALTQAR YLDKEEKCLP PPSIRVVVTV EQTDEELQRA AATIREAAQA VLL 473 
Gene Ontology
 GO:0035339; C:SPOTS complex; IEA:Compara.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0004758; F:serine C-palmitoyltransferase activity; IEA:Compara.
 GO:0046513; P:ceramide biosynthetic process; IEA:Compara.
 GO:0046511; P:sphinganine biosynthetic process; IEA:Compara.
 GO:0006686; P:sphingomyelin biosynthetic process; IEA:Compara.
 GO:0046512; P:sphingosine biosynthetic process; IEA:Compara. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
  
PRINTS