CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036011
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microtubule-associated protein 1B 
Protein Synonyms/Alias
  
Gene Name
 MAP1B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
276GGFLKLSKPCCYIFPubiquitination[1]
344INSMLQRKIAELEEEubiquitination[2]
383LNVPENLKNPEPNIKubiquitination[2]
521NILEGLEKLKHLDFLubiquitination[2]
536KQPLATQKDLTGQVPubiquitination[2]
548QVPTPVVKQTKLKQRubiquitination[2, 3]
579KSVRKESKEETPEVTubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 670 AA 
Protein Sequence
MATVVVEATE PEPSGSIANP AASTSPSLSH RFLDSKFYLL VVVGEIVTEE HLRRAIGNIE 60
LGIRSWDTNL IECNLDQELK LFVSRHSARF SPEVPGQKIL HHRSDVLETV VLINPSDEAV 120
STEVRLMITD AARHKLLVLT GQCFENTGEL ILQSGSFSFQ NFIEIFTDQE ILKGGHNKCP 180
VNLNFFKIGE LLSTTHPANK ASLTLFCPEE GDWKNSNLDR HNLQDFINIK LNSASILPEM 240
EGLSEFTEYL SESVEVPSPF DILEPPTSGG FLKLSKPCCY IFPGGRGDSA LFAVNGFNML 300
INGGSERKSC FWKLIRHLDR VDSILLTHIG DDNLPGINSM LQRKIAELEE EQSQGSTTNS 360
DWMKNLISPD LGVVFLNVPE NLKNPEPNIK MKRSIEEACF TLQYLNKLSM KPEPLFRSVG 420
NTIDPVILFQ KMGVGKLEMY VLNPVKSSKE MQYFMQQWTG TNKDKAEFIL PNGQEVDLPI 480
SYLTSVSSLI VWHPANPAEK IIRVLFPGNS TQYNILEGLE KLKHLDFLKQ PLATQKDLTG 540
QVPTPVVKQT KLKQRADSRE SLKPAAKPLP SKSVRKESKE ETPEVTKVNH VEKPPKVESK 600
EKVMVKKDKP IKTETKPSVT EKEVPSKEEP SPVKAEVAEK QATDVKPKAA KEKTVKKETK 660
VKPEDKKEEK 670 
Gene Ontology
 GO:0005874; C:microtubule; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR001279; Beta-lactamas-like.
 IPR026074; MAP1.
 IPR027321; MAP1B. 
Pfam
  
SMART
  
PROSITE
  
PRINTS