CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042800
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein 
Protein Synonyms/Alias
  
Gene Name
 PREX1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
29LLVATKAKEIIKIPDubiquitination[1]
248FRNICDTKLESIGQRubiquitination[1]
267QEFAAQLKSRVSPPFubiquitination[1]
391RGLSFLLKQEDREIQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 883 AA 
Protein Sequence
XPFSEVESIL NQSFCSRRPL RLLVATKAKE IIKIPDQPDT LCFQIRGAAP PYVYAVGRGS 60
EAMAAGLCAG QCILKVNGSN VMNDGAPEVL EHFQAFRSRR EEALGLYQWI YHTHEDAQEA 120
RASQEASTED PSGEQAQEED QADSAFPLLS LGPRLSLCED SPMVTLTVDN VHLEHGVVYE 180
YVSTAGVRCH VLEKIVEPRG CFGLTAKILE AFAANDSVFV ENCRRLMALS SAIVTMPHFE 240
FRNICDTKLE SIGQRIACYQ EFAAQLKSRV SPPFKQAPLE PHPLCGLDFC PTNCHINLME 300
VSYPKTTPSV GRSFSIRFGR KPSLIGLDPE QGHLNPMSYT QHCITTMAAP SWKCLPAAEG 360
DPQGQGLHDG SFGPASGTLG QEDRGLSFLL KQEDREIQDA YLQLFTKLDV ALKEMKQYVT 420
QINRLLSTIT EPTSGGSCDA SLAEEASSLP LVSEESEMDR SDHGGIKKVC FKVAEEDQED 480
SGHDTMSYRD SYSECNSNRD SVLSYTSVRS NSSYLGSDEM GSGDELPCDM RIPSDKQDKL 540
HGCLEHLFNQ VDSINALLKG PVMSRAFEET KHFPMNHSLQ EFKQKEECTI RGRSLIQISI 600
QEDPWNLPNS IKTLVDNIQR YVEDGKNQLL LALLKCTDTE LQLRRDAIFC QALVAAVCTF 660
SKQLLAALGY RYNNNGEYEE SSRDASRKWL EQVAATGVLL HCQSLLSPAT VKEERTMLED 720
IWVTLSELDN VTFSFKQLDE NYVANTNVFY HIEGSRQALK VIFYLDSYHF SKLPSRLEGG 780
ASLRLHTALF TKGELQAWGR EDHGGRAKAT KHTGSQPPAR PRHLPSQCWR TWRGCLLQAA 840
RPRRICSRTS TRSPWRKFSS ITANSGHFTW SGLTCPRMPA PRR 883 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. 
Interpro
 IPR001478; PDZ. 
Pfam
  
SMART
  
PROSITE
  
PRINTS