Tag | Content |
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CPLM ID | CPLM-006868 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 13 |
Protein Synonyms/Alias | Deubiquitinating enzyme 13; Ubiquitin thioesterase 13; Ubiquitin-specific-processing protease 13 |
Gene Name | UBP13 |
Gene Synonyms/Alias | YBL067C; YBL0621 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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469 | NSDSEPSKSKNFISD | ubiquitination | [1] | 571 | KRFKYSEKQNCNIKL | ubiquitination | [1] |
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Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | |
Sequence Annotation | ACT_SITE 149 149 Nucleophile (By similarity). ACT_SITE 619 619 Proton acceptor (By similarity). MOD_RES 198 198 Phosphoserine. |
Keyword | Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 747 AA |
Protein Sequence | MIRRWLTISK SGKKKKAVND TITEEVEKVD FKPVNHDIND ELCYSESSDN PSSSLFVSNL 60 DTKETFLNED NNLQISSGLD YSSETCNQGS NYSQDGIFYI SNAKAINAYG GIITQGPEAP 120 ILAMKVSDSM PYGDGSNKVF GYENFGNTCY CNSVLQCLYN LSSLRENILQ FPKKSRESDQ 180 PRKKEMRGKK PRIFTEASFE KSIAGTNGHL PNPKPQSVDD GKPTPVNSVN SNTAGPSEKK 240 SKFFKSFSAK HVQDNNKKEG SPAILTTGKP SSRPQDAPPL IVETPNEPGA PSRLSFENVT 300 DRPPDVPRKI IVGRVLNYEN PSRGSSNSNN LDLKGESNSS LSTPLDKKDT RRSSSSSQIS 360 PEHRKKSALI RGPVLNIDHS LNGSDKATLY SSLRDIFECI TENTYLTGVV SPSSFVDVLK 420 RENVLFNTTM HQDAHEFFNF LLNELSEYIE RENKKIAASD INSDSEPSKS KNFISDLFQG 480 TLTNQIKCLT CDNITSRDEP FLDFPIEVQG DEETDIQEIL KSYHQREMLN GSNKFYCDEC 540 CGLQEAERLV GLKQLPDTLT LHLKRFKYSE KQNCNIKLFN NIHYPLTLNV CSSINSKVCQ 600 KYELAGIVVH MGGGPQHGHY VSLCKHEKFG WLLFDDETVE AVKEETVLEF TGESPNMATA 660 YVLFYKAMYS NAVEKNDREN MAKEQDDNID NLIKYDDWLR TCNSGQKKKE ELPIADDLDT 720 AIDDSFVSNT PIKSSKKKSR MFSFRKS 747 |
Gene Ontology | GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |