CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024536
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger SWIM domain-containing protein 8 
Protein Synonyms/Alias
  
Gene Name
 ZSWIM8 
Gene Synonyms/Alias
 KIAA0913 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
460LKVIENVKRGQHKKTubiquitination[1]
503TYSGTDRKLALCWARubiquitination[1]
891EVAALLKKIPLGPSEubiquitination[1]
1385QRALVQCKEQDNLMLubiquitination[1]
1394QDNLMLEKACMAVEEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 ZN_FING 172 208 SWIM-type.
 MOD_RES 567 567 Phosphoserine.
 MOD_RES 1836 1836 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1837 AA 
Protein Sequence
MELMFAEWED GERFSFEDSD RFEEDSLCSF ISEAESLCQN WRGWRKQSAG PNSPTGGGGG 60
GGSGGTRMRD GLVIPLVELS AKQVAFHIPF EVVEKVYPPV PEQLQLRIAF WSFPENEEDI 120
RLYSCLANGS ADEFQRGDQL FRMRAVKDPL QIGFHLSATV VPPQMVPPKG AYNVAVMFDR 180
CRVTSCSCTC GAGAKWCTHV VALCLFRIHN ASAVCLRAPV SESLSRLQRD QLQKFAQYLI 240
SELPQQILPT AQRLLDELLS SQSTAINTVC GAPDPTAGPS ASDQSTWYLD ESTLTDNIKK 300
TLHKFCGPSP VVFSDVNSMY LSSTEPPAAA EWACLLRPLR GREPEGVWNL LSIVREMFKR 360
RDSNAAPLLE ILTDQCLTYE QITGWWYSVR TSASHSSASG HTGRSNGQSE VAAHACASMC 420
DEMVTLWRLA VLDPALSPQR RRELCTQLRQ WQLKVIENVK RGQHKKTLER LFPGFRPAVE 480
ACYFNWEEAY PLPGVTYSGT DRKLALCWAR ALPSRPGASR SGGLEESRDR PRPLPTEPAV 540
RPKEPGTKRK GLGEGVPSSQ RGPRRLSAEG GDKALHKMGP GGGKAKALGG AGSGSKGSAG 600
GGSKRRLSSE DSSLEPDLAE MSLDDSSLAL GAEASTFGGF PESPPPCPLH GGSRGPSTFL 660
PEPPDTYEED GGVYFSEGPE PPTASVGPPG LLPGDVCTQD DLPSTDESGN GLPKTKEAAP 720
AVGEEDDDYQ AYYLNAQDGA GGEEEKAEGG AGEEHDLFAG LKPLEQESRM EVLFACAEAL 780
HAHGYSSEAS RLTVELAQDL LANPPDLKVE PPPAKGKKNK VSTSRQTWVA TNTLSKAAFL 840
LTVLSERPEH HNLAFRVGMF ALELQRPPAS TKALEVKLAY QESEVAALLK KIPLGPSEMS 900
TMRCRAEELR EGTLCDYRPV LPLMLASFIF DVLCAPGSRP PSRNWNSETP GDEELGFEAA 960
VAALGMKTTV SEAEHPLLCE GTRREKGDLA LALMITYKDD QAKLKKILDK LLDRESQTHK 1020
PQTLSSFYSS SRPTTASQRS PSKHGGPSAP GALQPLTSGS AGPAQPGSVA GAGPGPTEGF 1080
TEKNVPESSP HSPCEGLPSE AALTPRPEGK VPSRLALGSR GGYNGRGWGS PGRPKKKHTG 1140
MASIDSSAPE TTSDSSPTLS RRPLRGGWAP TSWGRGQDSD SISSSSSDSL GSSSSSGSRR 1200
ASASGGARAK TVEVGRYKGR RPESHAPHVP NQPSEAAAHF YFELAKTVLI KAGGNSSTSI 1260
FTHPSSSGGH QGPHRNLHLC AFEIGLYALG LHNFVSPNWL SRTYSSHVSW ITGQAMEIGS 1320
AALTILVECW DGHLTPPEVA SLADRASRAR DSNMVRAAAE LALSCLPHAH ALNPNEIQRA 1380
LVQCKEQDNL MLEKACMAVE EAAKGGGVYP EVLFEVAHQW FWLYEQTAGG SSTAREGATS 1440
CSASGIRAGG EAGRGMPEGR GGPGTEPVTV AAAAVTAAAT VVPVISVGSS LYPGPGLGHG 1500
HSPGLHPYTA LQPHLPCSPQ YLTHPAHPAH PMPHMPRPAV FPVPSSAYPQ GVHPAFLGAQ 1560
YPYSVTPPSL AATAVSFPVP SMAPITVHPY HTEPGLPLPT SVACELWGQG TVSSVHPAST 1620
FPAIQGASLP ALTTQPSPLV SGGFPPPEEE THSQPVNPHS LHHLHAAYRV GMLALEMLGR 1680
RAHNDHPNNF SRSPPYTDDV KWLLGLAAKL GVNYVHQFCV GAAKGVLSPF VLQEIVMETL 1740
QRLSPAHAHN HLRAPAFHQL VQRCQQAYMQ YIHHRLIHLT PADYDDFVNA IRSARSAFCL 1800
TPMGMMQFND ILQNLKRSKQ TKELWQRVSL EMATFSP 1837 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR007527; Znf_SWIM. 
Pfam
  
SMART
  
PROSITE
 PS50966; ZF_SWIM 
PRINTS