CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038943
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mitochondrial intermediate peptidase 
Protein Synonyms/Alias
  
Gene Name
 Mipep 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
124ADLADFVKIGHPEQAacetylation[1]
167LQKLLDDKKLMDSLDacetylation[1]
542RVVSQFAKHYQTGQPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 710 AA 
Protein Sequence
MLLAAGTRYA YRLCGRRAAA ALQGHAGRSC ARSVSTSWSP VGAAFNVKPQ GHLWDLLGER 60
RGLFGVPELS TPEGFQVAQE EALRKTEWLV ERACSTPPGP QTVLIFDELS DCLCRVADLA 120
DFVKIGHPEQ AFREAAQEAC RSIGTMVEKL NTNVELYQSL QKLLDDKKLM DSLDAETRRV 180
AELFMFDFEI SGIHLDEEKR RRAVDLNVKI LDLSSAFLMG TNFPIKIQKH LLPEHIQHHF 240
ARDGRHLVID GLHAEASDDL VREAAYKIFL YPNADQLKCL EELLSSRDLL ANLVGYLPFP 300
TGPPGTIAQT PETVMQFLEK LSEKLCERTR KDFEMMQGMK TKLNPQNSEL MPWDPPYYSG 360
VIRAERYNIE PSLYCPFLSL GACMEGLNVL FNRLLGVTLY AEQPFKGEVW CIDVRKLAVV 420
HESEGLLGYI YCDFFQRANK PQQDCHFTIR GGRLKEDGSY QLPVVVLMLN LPHASRDFPT 480
LLTPGMMENL FHEMGHAMHS MLGRTRYQHV TGTRCPTDFA EVPSILMEYF SNDYRVVSQF 540
AKHYQTGQPL PKAMVSRLCE SKKVCAAAEM QLQVFYAALD QIYHGQHPLK KSTTDILMET 600
QEQFYGLPYV PDTAWQLRFS HLVGYGAKYY SYLMSRAVAS MVWKECFLQD PFNRAAGERY 660
RREMLAHGGG KEPMLMIQGM LQKCPSIDDF VDALVSDLNL DFETFFMDSK 710 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR024079; MetalloPept_cat_dom.
 IPR024077; Neurolysin/TOP_dom2.
 IPR024080; Neurolysin/TOP_N.
 IPR001567; Pept_M3A_M3B. 
Pfam
 PF01432; Peptidase_M3 
SMART
  
PROSITE
  
PRINTS