CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026749
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Multidomain chemotaxis histidine kinase CheA2 (Hpt, CheA, CheW, & Resp. Reg. Rec. domains) 
Protein Synonyms/Alias
 Multidomain chemotaxis histidine kinase CheA3 (Hpt, CheA, CheW, & Resp. Reg. Rec. domains) 
Gene Name
 cheA3 
Gene Synonyms/Alias
 cheA2; RPA1627; RPA1676 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
445MTEAQIHKFIFAPGFacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Phosphoprotein; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 937 AA 
Protein Sequence
MDDLLREFLT ETFESLDTVD NQLVRFEQEP NNAKILDNIF RLVHTIKGTC GFLGLPRLEA 60
LAHAAETLMG KFRDGMPVTG EAVTLILTTI DRIKDILTQL EATQAEPEGE DGDLIGELER 120
LSMRSPEEIA AELGGAAPVE VAEVEAPAEA VVAEAADANS TEGTLVAQTL ERPLRPGEVS 180
LDELERAFRE TEIEMASPPL QPAVSEAPAA VAEAAPPEPK PAKPAKPAAK PAAKKSGGEG 240
EGAAEGGAAG GVANQSIRVN VDTLEHLMTM VSELVLTRNQ LLEISRRHED NEFKVPLQRL 300
STVTAELQDG VMKTRMQPIG NAWQKLPRIV RDLAAELGKQ IELEMHGADT ELDRQVLDLI 360
KDPLTHMVRN SADHGLEKPE DRARAGKPEQ GTIRLSAYHE GGHIVICIAD NGRGLDTERI 420
KAKALANGLV TEAELEKMTE AQIHKFIFAP GFSTAAAVTS VSGRGVGMDV VRTNIDQIGG 480
TIEVKSVAGE GSAITIKIPL TLAIVSALIV EAGGDRFAIP QLAVVELVRA RANSEHRIER 540
IKDTPVLRLR DKLLPLIHLK KLLGIDEGAN SEPENGFIVV TQVGSQTFGI VVDGVFHTEE 600
IVVKPMSTKL RHIGMFSGNT ILGDGAVIMI VDPNGIAQAL GTAVSAQHDI SDQAAASRNA 660
SAEQLTSLLV FRAGSSQPKA VPLSLVTRLE EIASDKIEMS NGRYMVQYRD QLMPLVLMEG 720
VEVATSGVQP ILVFADEDRS MGLVVDEIVD IVEEHLHIQV GSSREGILGS AVIKGQATEV 780
IDVAHFLPMA FSDWLARKEM KQSLTTRSVL LVDDSAFFRN MLGPVLKAAG YKVRVATSAV 840
EGLSVLRSGA QFDVILTDIE MPEMNGFEFA EAIRSDTKMS NLPVIALSSL VSPAAIERGR 900
QAGLTDYIAK FDRPGLIAAL KEQTTMHATP EVLEQAA 937 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
 GO:0006935; P:chemotaxis; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0023014; P:signal transduction by phosphorylation; IEA:GOC. 
Interpro
 IPR002545; CheW.
 IPR011006; CheY-like_superfamily.
 IPR003594; HATPase_ATP-bd.
 IPR004358; Sig_transdc_His_kin-like_C.
 IPR008207; Sig_transdc_His_kin_Hpt_dom.
 IPR004105; Sig_transdc_His_kin_subgr_dim.
 IPR005467; Sig_transdc_His_kinase_core.
 IPR009082; Sig_transdc_His_kinase_dimeric.
 IPR001789; Sig_transdc_resp-reg_receiver. 
Pfam
 PF01584; CheW
 PF02895; H-kinase_dim
 PF02518; HATPase_c
 PF01627; Hpt
 PF00072; Response_reg 
SMART
 SM00260; CheW
 SM00387; HATPase_c
 SM00073; HPT
 SM00448; REC 
PROSITE
 PS50851; CHEW
 PS50109; HIS_KIN
 PS50894; HPT
 PS50110; RESPONSE_REGULATORY 
PRINTS
 PR00344; BCTRLSENSOR.