CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029443
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 55 kDa erythrocyte membrane protein 
Protein Synonyms/Alias
  
Gene Name
 MPP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
101TKGMISLKVIPNQQSubiquitination[1]
134KDNLIPCKEAGLKFAubiquitination[1]
151DIIQIINKDDSNWWQubiquitination[1]
166GRVEGSSKESAGLIPacetylation[2]
166GRVEGSSKESAGLIPubiquitination[1, 2]
201PSCSPFGKKKKYKDKubiquitination[1, 3]
202SCSPFGKKKKYKDKYubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 241 AA 
Protein Sequence
MYTNGSPAPG SPAQVKGQEV RKVRLIQFEK VTEEPMGITL KLNEKQSCTV ARILHGGMIH 60
RQGSLHVGDE ILEINGTNVT NHSVDQLQKA MKETKGMISL KVIPNQQSRL PALQMFMRAQ 120
FDYDPKKDNL IPCKEAGLKF ATGDIIQIIN KDDSNWWQGR VEGSSKESAG LIPSPELQEW 180
RVASMAQSAP SEAPSCSPFG KKKKYKDKYL AKHSSIFDQL DVVSYEEVVR LPAFKRKTLV 240
L 241 
Gene Ontology
 GO:0030863; C:cortical cytoskeleton; IEA:Compara.
 GO:0016020; C:membrane; IEA:Compara.
 GO:0090022; P:regulation of neutrophil chemotaxis; IEA:Compara. 
Interpro
 IPR001478; PDZ.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF00595; PDZ
 PF07653; SH3_2 
SMART
 SM00228; PDZ
 SM00326; SH3 
PROSITE
 PS50106; PDZ
 PS50002; SH3 
PRINTS