UniProt Accession

 AAAS_HUMAN; Q9NRG9; Q5JB47; Q9NWI6; Q9UG19 

Genbank Protein ID

 AJ289857; AJ289841; AJ289842; AJ289843; AJ289844; AJ289845; AJ289846; AJ289847; AJ289848; AJ289849; AJ289850; AJ289851; AJ289852; AJ289853; AJ289854; AJ289855; AJ289856; AJ297977; AY237818; AF226048; AK000833; BT006912; AC073611; BC000659; AL110160 

Genbank Nucleotide ID

 CAC19017.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC19038.1; CAC17465.1; AAP69911.1; AAF86948.1; BAA91394.1; AAP35558.1; AAH00659.1; CAB53665.2 

Protein Name

 Aladin 

Protein Synonyms/Alias

 Adracalin 

Gene Name

 AAAS 

Gene Synonyms/Alias

 ADRACALA; GL003 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
156	CTIVPSLKHRLQRNV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Plays a role in the normal development of the peripheral and central nervous system. 

Sequence Annotation

 REPEAT 149 188 WD 1.
 REPEAT 191 230 WD 2.
 REPEAT 243 282 WD 3.
 REPEAT 285 324 WD 4.
 MOTIF 544 546 Microbody targeting signal (Potential).
 MOD_RES 33 33 Phosphoserine.
 MOD_RES 495 495 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Disease mutation; Phosphoprotein; Reference proteome; Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 546 AA 

Protein Sequence

Gene Ontology

 GO:0005813; C:centrosome; IDA:HPA.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0005643; C:nuclear pore; IDA:MGI.
 GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
 GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
 GO:0009566; P:fertilization; IEA:Compara.
 GO:0015758; P:glucose transport; TAS:Reactome.
 GO:0007612; P:learning; IEA:Compara.
 GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.
 GO:0010827; P:regulation of glucose transport; TAS:Reactome.
 GO:0046822; P:regulation of nucleocytoplasmic transport; NAS:UniProtKB.
 GO:0044281; P:small molecule metabolic process; TAS:Reactome.
 GO:0055085; P:transmembrane transport; TAS:Reactome.
 GO:0022415; P:viral reproductive process; TAS:Reactome. 

Interpro

 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF00400; WD40 

SMART

 SM00320; WD40 

PROSITE

 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS