UniProt Accession

 IN4L2_HUMAN; Q2T9F4 

Genbank Protein ID

 BC111554 

Genbank Nucleotide ID

 AAI11555.1 

Protein Name

 Integrator complex subunit 4-like protein 2 

Protein Synonyms/Alias

  

Gene Name

 INTS4L2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
94	VVHVQAAKLLGSMEQ	ubiquitination	[1]
114	LEQTLDKKLMSDLRR	ubiquitination	[1]
130	RTAHERAKELYSSGE	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 REPEAT 160 197 HEAT 1.
 REPEAT 198 234 HEAT 2.
 REPEAT 236 270 HEAT 3.
 REPEAT 306 346 HEAT 4.  

Keyword

 Complete proteome; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 439 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 

Pfam

  

SMART

  

PROSITE

 PS50077; HEAT_REPEAT 

PRINTS