UniProt Accession

 ORML1_HUMAN; Q9P0S3; B2R8W3; D3DPH9 

Genbank Protein ID

 AF395702; AF395701; AF395704; AB064959; AB064960; AF151036; AK074756; AK075160; AK313533; CR936635; AC013468; CH471058; CH471058; CH471058; BC005200 

Genbank Nucleotide ID

 AAM43502.1; AAM43502.1; AAM43503.1; BAC11710.1; BAC11711.1; AAF36122.1; BAC11184.1; BAC11441.1; BAG36310.1; CAI56776.1; AAY14772.1; EAX10887.1; EAX10888.1; EAX10889.1; AAH05200.1 

Protein Name

 ORM1-like protein 1 

Protein Synonyms/Alias

 Adoplin-1 

Gene Name

 ORMDL1 

Gene Synonyms/Alias

 HSPC202 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
79	FETPDQGKARLLTHW	ubiquitination	[1]
152	VRIFGINKY******	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Negative regulator of sphingolipid synthesis. 

Sequence Annotation

  

Keyword

 Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 153 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0006672; P:ceramide metabolic process; IMP:UniProtKB. 

Interpro

 IPR007203; ORMDL. 

Pfam

 PF04061; ORMDL 

SMART

  

PROSITE

  

PRINTS