CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039392
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Caseinolytic peptidase B protein homolog 
Protein Synonyms/Alias
  
Gene Name
 Clpb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
283AREGEVMKLLKTSETacetylation[1]
593HYGARSIKHEVERRVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 677 AA 
Protein Sequence
MMLSAVLRRT APAPRLFLGL IKSPSLQSRG GAYNRSVITG DRGEPQRLRT AAWVRPGASS 60
VLFPGRGAAT GGRRGERTEI PYLTAASSGR GPSPEETLPG QDSWNGVPNK AGLGMWGLFL 120
ALRGWSLTST PLFSDAALME AARANNVQEV RRLLSEGADV NARHKLGWTA LMVAAISHNE 180
SVVQVLLAAG ADPNLGDDFS SVYKTANEQG VHSLEVLVTR EDDFNNRLNH RASFKGCTAL 240
HYAVLADDYS IVKELLGGGA NPLQRNEMGH TPLDYAREGE VMKLLKTSET KYMEKQRKRE 300
AEERRRFPLE QRLKEHIIGQ ESAIATVGAA IRRKENGWYD EEHPLVFLFL GSSGIGKTEL 360
AKQTAKYMHK DAKKGFIRLD MSEFQERHEV AKFIGSPPGY IGHEEGGQLT KKLKQCPNAV 420
VLFDEVDKAH PDVLTIMLQL FDEGRLTDGK GKTIDCKDAI FIMTSNVASD EIAQHALQLR 480
QEALEMSRNR IAENLGDVQI SDKITISKNF KENVIRPILK AHFRRDEFLG RINEIVYFLP 540
FCHSELIQLV NKELNFWAKR AKQRHNITLL WDREVADVLV DGYNVHYGAR SIKHEVERRV 600
VNQLAAAYEQ DLLPGGCTLR ITVEDSDKQL LKSPELPSPQ AEKRPPTLRL EIIDKDSKTH 660
KLDIQAPLHP EKVCYTI 677 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0034605; P:cellular response to heat; IEA:Compara. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR013093; ATPase_AAA-2.
 IPR001270; Chaprnin_ClpA/B.
 IPR019489; Clp_ATPase_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF07724; AAA_2
 PF00023; Ank
 PF12796; Ank_2
 PF10431; ClpB_D2-small 
SMART
 SM00382; AAA
 SM00248; ANK
 SM01086; ClpB_D2-small 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR00300; CLPPROTEASEA.