Tag | Content |
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CPLM ID | CPLM-024625 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Disks large-associated protein 4 |
Protein Synonyms/Alias | DAP-4; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4; SAPAP-4 |
Gene Name | Dlgap4 |
Gene Synonyms/Alias | Kiaa0964; Sapap4 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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827 | GWCCQMDKETKENNL | acetylation | [1] |
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Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane (By similarity). |
Sequence Annotation | MOD_RES 367 367 Phosphoserine. MOD_RES 377 377 Phosphoserine. MOD_RES 397 397 Phosphoserine. MOD_RES 421 421 Phosphoserine. MOD_RES 512 512 Phosphoserine. MOD_RES 665 665 Phosphoserine. MOD_RES 915 915 Phosphothreonine. MOD_RES 973 973 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; Membrane; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 992 AA |
Protein Sequence | MKGLGDSRPR HLSDSLDPPH EPLFAGPDRN PYLLSPTEAF AREARFPGQN TLPGDGLFPL 60 NNQLPPPSST FPRIHYNSHF EVPEESPFPS HAQATKINRL PANLLDQFEK QLPIHRDGFS 120 TLQFPRGEAK ARGESPGRIR HLVHSVQRLF FTKAPSMEGT AGKVGGNGSK KGGLEDGKGR 180 RAKSKERAKA GEPKRRSRSN ISGWWSSDDN LDGEGGAFRS GPASGLMTLG RQQERTQPRY 240 FMHAYNTISG HMLKTTKNTT TELTAPPPPP APPATCPSLG VGTDTNYVKR GSWSTLTLSH 300 AHEVCQKTSA TLDKSLLKSK SCHQGLAYHY LQVPGGGGEW STTLLSPRDM DSTAEGPIPC 360 RRMRSGSYIK AMGDEDSDES GGGSPKPSPK TAARRQSYLR ATQQSLGEQS NPRRSLDRLD 420 SVDMLLPSKC PSWEDDYNPI SDSLNDSSCI SQVFGQASLI PQLFGHDQQV READLSDQYE 480 AACESACSEA ESTTAEALDL PLPSYFRSRS HSYLRAIQAG CSQEEDSVSL QSLSPPPSTG 540 SLSNSRTLPS SSCLVAYKKT PPPVPPRTTS KPFISVTVQS STESAQDTYL DSQDHKSEVT 600 SQSGLSNSSD SLDSSTRPPS VTRGGITPGP EAPEPPPKHA ALKSEQGTLT SSESHSEAIP 660 KRKLSSIGIQ VDCIQPVPKE EPSPATKFQS IGIQVEDDWR SSAPSHSMSS RRDTDSDTQD 720 ANDSSCKSSE RSLPDCTSHP NSISIDAGPR QAPKIAQIKR NLSYGDNSDP ALEASSLPPP 780 DPWLETSSSS PAEPAQPGAC RRDGYWFLKL LQAETERLEG WCCQMDKETK ENNLSEEVLG 840 KVLSAVGSAQ LLMSQKFQQF RGLCEQNLNP DANPRPTAQD LAGFWDLLQL SIEDISMKFD 900 ELYHLKANSW QLVETPEKRK EEKKPPPPVP KKPAKSKAAV SRDKASDAGD KQRQEARKRL 960 LAAKRAASVR QNSATESADS IEIYVPEAQT RL 992 |
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