UniProt Accession

 PRVA_RAT; P02625; A0JN21 

Genbank Protein ID

 M12725; M15457; M15453; M15454; M15455; BC126090; M10764; M10765 

Genbank Nucleotide ID

 AAA41799.1; AAA41800.1; AAA41800.1; AAA41800.1; AAA41800.1; AAI26091.1; AAA41797.1; AAA41798.1 

Protein Name

 Parvalbumin alpha 

Protein Synonyms/Alias

  

Gene Name

 Pvalb 

Gene Synonyms/Alias

 Pva 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
13	LLSAEDIKKAIGAFT	acetylation	[1]
14	LSAEDIKKAIGAFTA	acetylation	[1]
29	ADSFDHKKFFQMVGL	acetylation	[1]
37	FFQMVGLKKKSADDV	acetylation	[1]
46	KSADDVKKVFHILDK	acetylation	[1]
55	FHILDKDKSGFIEED	acetylation	[1]
81	DARDLSAKETKTLMA	acetylation	[1]
84	DLSAKETKTLMAAGD	acetylation	[1]
92	TLMAAGDKDGDGKIG	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. 

Sequence Annotation

 DOMAIN 39 74 EF-hand 1.
 DOMAIN 78 110 EF-hand 2.
 MOD_RES 2 2 N-acetylserine.
 MOD_RES 73 73 Phosphoserine (By similarity).
 MOD_RES 79 79 Phosphoserine (By similarity).
 MOD_RES 83 83 Phosphothreonine (By similarity).  

Keyword

 3D-structure; Acetylation; Calcium; Complete proteome; Direct protein sequencing; Metal-binding; Muscle protein; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 110 AA 

Protein Sequence

Gene Ontology

 GO:0030424; C:axon; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0005509; F:calcium ion binding; IDA:RGD.
 GO:0046982; F:protein heterodimerization activity; IDA:RGD.
 GO:0042803; F:protein homodimerization activity; IDA:RGD.
 GO:0051480; P:cytosolic calcium ion homeostasis; IDA:RGD. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR008080; Parvalbumin. 

Pfam

 PF13499; EF_hand_5 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS