UniProt Accession

 AKIP1_HUMAN; Q9NQ31; Q8NBS2; Q8TAC6; Q8TAD3; Q8TAE0 

Genbank Protein ID

 AF493783; AF493784; AF493785; AF493786; AF493786; AF493786; AF512007; AJ400877; AK075308; BC030996 

Genbank Nucleotide ID

 AAM12862.1; AAM12863.1; AAM12864.1; AAM12865.1; AAM12866.1; AAM12867.1; AAM34785.1; CAB92290.1; BAC11537.1; AAH30996.1 

Protein Name

 A-kinase-interacting protein 1 

Protein Synonyms/Alias

 Breast cancer-associated gene 3 protein; PKA-interacting protein; Proline-rich protein BCA3 

Gene Name

 AKIP1 

Gene Synonyms/Alias

 BCA3; C11orf17 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
46	WHALERPKGCMGVLA	ubiquitination	[1]
61	REAPHLEKQPAAGPQ	ubiquitination	[1]
75	QRVLPGEKYYSSVPE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Nucleus; Polymorphism; Proto-oncogene; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 210 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS