CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026484
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kelch-like protein 8 
Protein Synonyms/Alias
 Putative uncharacterized protein DKFZp781C1855 
Gene Name
 DKFZp781C1855 
Gene Synonyms/Alias
 KLHL8 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
72ELCDVTLKVRLPLLPubiquitination[1]
94VAKEQIVKQNLKCRDubiquitination[1]
160IECYSINKNSWFFGPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kelch repeat; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 437 AA 
Protein Sequence
MASDSMSSKQ ARNHITKGKR QQQHQQIKNR SSISDGDGED SFIFEANEAW KDFHGSLLRF 60
YENGELCDVT LKVRLPLLPV DFLMGVVAKE QIVKQNLKCR DLLDEARNYH LHLSSRAVPD 120
FEYSIRTTPR KHTAGVLFCV GGRGGSGDPF RSIECYSINK NSWFFGPEMN SRRRHVGVIS 180
VEGKVYAVGG HDGNEHLGSM EMFDPLTNKW MMKASMNTKR RGIALASLGG PIYAIGGLDD 240
NTCFNDVERY DIESDQWSTV APMNTPRGGV GSVALVNHVY AVGGNDGMAS LSSVERYDPH 300
LDKWIEVKEM GQRRAGNGVS KLHGCLYVVG GFDDNSPLSS VERYDPRSNK WDYVAALTTP 360
RGGVGIATVM GKIFAVGGHN GNAYLNTVEA FDPVLNRWEL VGSVSHCRAG AGVAVCSCLT 420
SQIRDVGHGS NNVVDCM 437 
Gene Ontology
  
Interpro
 IPR015916; Gal_Oxidase_b-propeller.
 IPR006652; Kelch_1. 
Pfam
 PF01344; Kelch_1 
SMART
 SM00612; Kelch 
PROSITE
  
PRINTS