CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004567
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 
Protein Synonyms/Alias
 Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 
Gene Name
 murG 
Gene Synonyms/Alias
 b0090; JW0088 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
284LFVPFQHKDRQQYWNacetylation[1]
297WNALPLEKAGAAKIIacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II). 
Sequence Annotation
  
Keyword
 3D-structure; Cell cycle; Cell division; Cell inner membrane; Cell membrane; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Direct protein sequencing; Glycosyltransferase; Membrane; Peptidoglycan synthesis; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 355 AA 
Protein Sequence
MSGQGKRLMV MAGGTGGHVF PGLAVAHHLM AQGWQVRWLG TADRMEADLV PKHGIEIDFI 60
RISGLRGKGI KALIAAPLRI FNAWRQARAI MKAYKPDVVL GMGGYVSGPG GLAAWSLGIP 120
VVLHEQNGIA GLTNKWLAKI ATKVMQAFPG AFPNAEVVGN PVRTDVLALP LPQQRLAGRE 180
GPVRVLVVGG SQGARILNQT MPQVAAKLGD SVTIWHQSGK GSQQSVEQAY AEAGQPQHKV 240
TEFIDDMAAA YAWADVVVCR SGALTVSEIA AAGLPALFVP FQHKDRQQYW NALPLEKAGA 300
AKIIEQPQLS VDAVANTLAG WSRETLLTMA ERARAASIPD ATERVANEVS RVARA 355 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0051991; F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity; IEA:EC.
 GO:0050511; F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity; IDA:EcoliWiki.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0030259; P:lipid glycosylation; IEA:HAMAP.
 GO:0009252; P:peptidoglycan biosynthetic process; IMP:EcoCyc.
 GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
 GO:0019277; P:UDP-N-acetylgalactosamine biosynthetic process; IEA:InterPro. 
Interpro
 IPR006009; GlcNAc_MurG.
 IPR004276; Glyco_trans_28.
 IPR007235; Glyco_trans_28_C. 
Pfam
 PF04101; Glyco_tran_28_C
 PF03033; Glyco_transf_28 
SMART
  
PROSITE
  
PRINTS