CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032488
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Ptprz1 
Protein Synonyms/Alias
 Protein tyrosine phosphatase, receptor type Z, polypeptide 1 
Gene Name
 Ptprz1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1699DIGAIPIKHFPKHVAubiquitination[1]
1765AYDHSRVKLTQLAEKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Receptor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2312 AA 
Protein Sequence
MRILQSFLAC VQLLCLCRLD WAYGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPICNSPK 60
QSPINIDEDL TQVNVNLKKL KFQGWEKASL ENTFIHNTGK TVEINLTNDY YLSGGLSEKV 120
FKASKITFHW GKCNVSSEGS EHSLEGQKFP LEMQVYCFDA DRFSSFEEAV KGKGRLRALS 180
ILFEVGVEEN LDYKAIIDGT ESVSRFGKQA ALDPFVLQNL LPNSTDKYYI YNGSLTSPPC 240
TDTVEWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300
TGKEEIHEVV CSSEPENVQA DPENYTSLLV TWERPRVVYD AMIEKFAVLY QPLAGNDQAK 360
HEFLTDGYQD LGAILNNLLP NMSYVLQIVA VCSNGLYGKY SDQLIVDMPT EDAELDLFPE 420
LIGTEEIIKE EEYGKDNEED TGLNPGRDSV TNQIRKKEPQ VSTTTHYNHM GTKYNEAKTN 480
RSPTRGSEFS GKSDVPNTSP NSTSQHVAEF ETERGISLPS QTGTNLPPHN VEGTSASLNS 540
GSKTLFIFPQ MNLSGTAESL NTVPITEYKE VSADVSEEEN FLTDFKLDTG ADDSSGSSPS 600
TSTVPFSSDN LSHGYITSSD MPEAITYDVL KPGSTRNAPE DSAPSGSEES LKDPSLEGSV 660
WFPGSTDLTT QSETGSGRES FLQVNSTDIQ IDESRETTES FSPDATVSQD PSVTDMGMPH 720
YSTFAYLPTE VTPQAFTPSS RPLDLAPTIN ILHSQTTQPV YNGETPLQPS YSSEVFPLAT 780
PLLLDNQTLN TTPAASSSDS ALHATPVSPS VGVSFESILS SYDDAPLLPF SSASFSSEMF 840
RHLHTVSQTL PQVTSAAERD ELSLHASLLV ARGDLLLEPS LVQYSDVASH QATTRAASDT 900
LGFGSESAVF YKTSMVSQIE SPRSDVVMHA YSSGPEPSYT VEGSHHVPTV SYSSAMPLHG 960
SVDVSDQGSL LINPSHISMP ESSFITPTAS LLQPPPALSG DGEWSGASSD SELLLPDADG 1020
LRTLNISSPV SVAEFTYTTS VFADGIKPLS KSEMMYGNET ELKMSSFSDM AYPSKSTVVP 1080
KMSDVVHKWS ESLKETSVSI SSMKSVFPES LVYPTTKGFE QGVSHVPEII FPVQPTHTAS 1140
QASGDTWLKP GLSANSEAAF SDTASREVVH PSTQPLLYEA ATPFNTEALL QPSFQASDVD 1200
TLLKTALPSV PSDPILAGTP QVEQSSSSVS HPMASESGSS ESMLHFTSVP ILDISPSKVH 1260
STPLQGLTVP HSSKKFSEQG LLKSKSPQQV LPSLFSNDEF FQSAHLDVSQ AYPPKGRHAF 1320
VTPVLSIDEP QNTLINKLVY SEDIFSSTEI SITDKVLTGL PTLASDVLSS TDHSVPLGSG 1380
PISLTMVSPN RDDSVTTAKL LLPSTATSKL TQSARSDADL VGGGEDGDDY DDDDYDDIDR 1440
GRFPVNKCMS CLPYRESREK VMNDSDTQES SLVDQSDPIS PLLFENTEEE NGGTGVTRVD 1500
KSPPPSMLPQ NHNDGKEDSD IQMGSAVLPH TPGSKAWAVL TSDEESGSGQ GTSDSLNDNE 1560
TSTDFSFPDV NEKDTDGVLE TDDTGIAPGS PRSSTPSVTS GHSGVSNSSE AEASNSSHES 1620
RIGLAEGLES EKKAVIPLVI VSALTFICLV VLVGILIYWR KCFQTAHFYL EDNTSPRVIS 1680
TPPTPIFPIS DDIGAIPIKH FPKHVADLHA SNGFTEEFET LKEFYQEVQS CTADLGITAD 1740
SSNHPDNKHK NRYVNIVAYD HSRVKLTQLA EKDGKLTDYI NANYVDGYNR PKAYIAAQGP 1800
LKSTAEDFWR MIWEHNVEVI VMITNLVEKG RRKCDQYWPT DGSEEYGSFL VNQKSVQVLA 1860
YYTVRNFTLR NTKLKKGSQK GRSSGRLVTQ YHYTQWPDMG VPEYSLPVLA FVRKAAQAKR 1920
HAVGPVVVHC SAGVGRTGTY IVLDSMLQQI QHEGTVNIFG FLKHIRSQRN YLVQTEEQYV 1980
FIHDTLVEAI LSKETEVPDS HIHSYVNTLL IPGPTGKTKL EKQFQLLSQS NILQSDYSTA 2040
LKQCNREKNR TSSIIPVERS RVGISSLSGE GTDYINASYI MGYYQSNEFI ITQHPLLHTI 2100
KDFWRMIWDH NAQLVVMIPD GQNMAEDEFV YWPNKDEPIN CESFKVTLMS EEHKCLSNEE 2160
KLIVQDFILE ATQDDYVLEV RHFQCPKWPN PDSPISKTFE LISIIKEEAA NRDGPMIVHD 2220
EHGGVTAGTF CALTTLMHQL EKENAMDVYQ VAKMINLMRP GVFTDIEQYQ FLYKVVLSLV 2280
STRQEENPST SLDSNGAALP DGNIAESLES LV 2312 
Gene Ontology
 GO:0072534; C:perineuronal net; IDA:MGI.
 GO:0005578; C:proteinaceous extracellular matrix; IDA:MGI.
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0007409; P:axonogenesis; IDA:MGI.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR001148; Carbonic_anhydrase_a.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF00194; Carb_anhydrase
 PF00041; fn3
 PF00102; Y_phosphatase 
SMART
 SM01057; Carb_anhydrase
 SM00060; FN3
 SM00194; PTPc 
PROSITE
 PS51144; ALPHA_CA_2
 PS50853; FN3
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00700; PRTYPHPHTASE.