CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011682
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Agmatinase, mitochondrial 
Protein Synonyms/Alias
 Agmatine ureohydrolase; AUH 
Gene Name
 Agmat 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
194AHSNTSDKPLEDKVYacetylation[1]
218DEGLLDSKRVVQIGIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 METAL 163 163 Manganese 1 (By similarity).
 METAL 188 188 Manganese 2 (By similarity).
 METAL 279 279 Manganese 2 (By similarity).  
Keyword
 Complete proteome; Hydrolase; Manganese; Metal-binding; Mitochondrion; Putrescine biosynthesis; Reference proteome; Spermidine biosynthesis; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 353 AA 
Protein Sequence
MLQLLKSSWV RSAGSGVVTW RASAGLFCPG TRQASDTSDT LHHPSPSSES QVQPVRVCSM 60
MHLPLQSSPE GLDAAFVGVP LDTGTSNRPG ARFGPRRIRE ESLMLGTVNP STGALPFQSL 120
RVADLGNVNV NLYNLQDSCR LIREAYQNIL ATGCIPLTLG GDHTITYPIL QAVAKEHGPV 180
GLVHVGAHSN TSDKPLEDKV YHRTPFRRSV DEGLLDSKRV VQIGIRGSSR TLDPYRYSRS 240
QGFRVVLAED CWMKSLVPLM AEIRQQMGGV PLYISFAIDA LDPAYAPGTG TPEIAGLTPS 300
QALEIIRGCQ GLNVVGCDLV EVSPPYDLSG NTALLAANLL FEMLCALPKV TTV 353 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0008783; F:agmatinase activity; IEA:EC.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0033388; P:putrescine biosynthetic process from arginine; IEA:UniProtKB-UniPathway.
 GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR005925; Agmatinase-rel.
 IPR006035; Ureohydrolase.
 IPR023696; Ureohydrolase_domain. 
Pfam
 PF00491; Arginase 
SMART
  
PROSITE
 PS01053; ARGINASE_1
 PS51409; ARGINASE_2 
PRINTS
 PR00116; ARGINASE.