UniProt Accession

 M0QW69_MOUSE; M0QW69 

Genbank Protein ID

 AC124686 

Genbank Nucleotide ID

  

Protein Name

 Methionine aminopeptidase 

Protein Synonyms/Alias

  

Gene Name

 Metap2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
139	DILLTAVKDATNTGI	ubiquitination	[1]
147	DATNTGIKCAGIDVR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Removes the N-terminal methionine from nascent proteins (By similarity). 

Sequence Annotation

  

Keyword

 Aminopeptidase; Cobalt; Complete proteome; Hydrolase; Metal-binding; Protease; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 186 AA 

Protein Sequence

Gene Ontology

 GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
 GO:0009987; P:cellular process; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 

Interpro

 IPR001714; Pept_M24_MAP.
 IPR000994; Pept_M24_structural-domain.
 IPR002468; Pept_M24A_MAP2.
 IPR018349; Pept_M24A_MAP2_BS. 

Pfam

 PF00557; Peptidase_M24 

SMART

  

PROSITE

 PS01202; MAP_2 

PRINTS

 PR00599; MAPEPTIDASE.