CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007716
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ABC transporter ATP-binding protein uup 
Protein Synonyms/Alias
  
Gene Name
 uup 
Gene Synonyms/Alias
 ycbH; ycbI; b0949; JW0932 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
47AGKSTLMKILNREQGacetylation[1]
115VMNDPSEKNLNELAKacetylation[1]
122KNLNELAKVQEQLDHacetylation[1]
336VNGKQLVKDFSAQVLacetylation[1]
363CGKTTLLKLMLGQLQacetylation[1]
398RAELDPDKTVMDNLAacetylation[1]
432QDFLFHPKRAMTPVRacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 253 ABC transporter 1.
 DOMAIN 320 546 ABC transporter 2.
 NP_BIND 36 43 ATP 1 (Potential).
 NP_BIND 352 359 ATP 2 (Potential).  
Keyword
 3D-structure; ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Repeat; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 635 AA 
Protein Sequence
MSLISMHGAW LSFSDAPLLD NAELHIEDNE RVCLVGRNGA GKSTLMKILN REQGLDDGRI 60
IYEQDLIVAR LQQDPPRNVE GSVYDFVAEG IEEQAEYLKR YHDISRLVMN DPSEKNLNEL 120
AKVQEQLDHH NLWQLENRIN EVLAQLGLDP NVALSSLSGG WLRKAALGRA LVSNPRVLLL 180
DEPTNHLDIE TIDWLEGFLK TFNGTIIFIS HDRSFIRNMA TRIVDLDRGK LVTYPGNYDQ 240
YLLEKEEALR VEELQNAEFD RKLAQEEVWI RQGIKARRTR NEGRVRALKA MRRERGERRE 300
VMGTAKMQVE EASRSGKIVF EMEDVCYQVN GKQLVKDFSA QVLRGDKIAL IGPNGCGKTT 360
LLKLMLGQLQ ADSGRIHVGT KLEVAYFDQH RAELDPDKTV MDNLAEGKQE VMVNGKPRHV 420
LGYLQDFLFH PKRAMTPVRA LSGGERNRLL LARLFLKPSN LLILDEPTND LDVETLELLE 480
ELIDSYQGTV LLVSHDRQFV DNTVTECWIF EGGGKIGRYV GGYHDARGQQ EQYVALKQPA 540
VKKTEEAAAA KAETVKRSSS KLSYKLQREL EQLPQLLEDL EAKLEALQTQ VADASFFSQP 600
HEQTQKVLAD MAAAEQELEQ AFERWEYLEA LKNGG 635 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:EcoCyc.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IDA:EcoCyc.
 GO:0003677; F:DNA binding; IDA:EcoCyc.
 GO:0070894; P:regulation of transposon integration; IMP:EcoCyc.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS