UniProt Accession

 MUP2_MOUSE; P11589; Q99JF6 

Genbank Protein ID

 M16356; AJ309921; BC012259; BC059097 

Genbank Nucleotide ID

 AAA39768.1; CAC34259.1; AAH12259.1; AAH59097.1 

Protein Name

 Major urinary protein 2 

Protein Synonyms/Alias

 MUP 2 

Gene Name

 Mup2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
154	DIKERFAKLCEEHGI	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. 

Sequence Annotation

 DISULFID 82 175 By similarity.  

Keyword

 3D-structure; Complete proteome; Disulfide bond; Pheromone-binding; Reference proteome; Secreted; Signal; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005615; C:extracellular space; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0005009; F:insulin-activated receptor activity; ISS:UniProtKB.
 GO:0005550; F:pheromone binding; ISS:UniProtKB.
 GO:0036094; F:small molecule binding; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0009060; P:aerobic respiration; ISS:UniProtKB.
 GO:0071396; P:cellular response to lipid; ISS:UniProtKB.
 GO:0006112; P:energy reserve metabolic process; ISS:UniProtKB.
 GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
 GO:0031649; P:heat generation; ISS:UniProtKB.
 GO:0045475; P:locomotor rhythm; ISS:UniProtKB.
 GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.
 GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.
 GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
 GO:0051055; P:negative regulation of lipid biosynthetic process; ISS:UniProtKB.
 GO:0010888; P:negative regulation of lipid storage; ISS:UniProtKB.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
 GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
 GO:0010907; P:positive regulation of glucose metabolic process; ISS:UniProtKB.
 GO:0045834; P:positive regulation of lipid metabolic process; ISS:UniProtKB.
 GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB. 

Interpro

 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR002345; Lipocalin.
 IPR022272; Lipocalin_CS.
 IPR000566; Lipocln_cytosolic_FA-bd_dom.
 IPR002971; Maj_urinary. 

Pfam

 PF00061; Lipocalin 

SMART

  

PROSITE

 PS00213; LIPOCALIN 

PRINTS

 PR00179; LIPOCALIN.
 PR01221; MAJORURINARY.