UniProt Accession

 QCR7_MOUSE; Q9D855; Q8K2E2 

Genbank Protein ID

 AK008455; BC031607 

Genbank Nucleotide ID

 BAB25678.1; AAH31607.1 

Protein Name

 Cytochrome b-c1 complex subunit 7 

Protein Synonyms/Alias

 Complex III subunit 7; Complex III subunit VII; Ubiquinol-cytochrome c reductase complex 14 kDa protein 

Gene Name

 Uqcrb 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
12	SAVSASSKWLDGFRK	acetylation	[1, 2]
45	LHETEDVKEAIRRLP	acetylation	[2]
78	MRHQILPKDQWTKYE	acetylation	[2]
83	LPKDQWTKYEEDKFY	acetylation	[2]
88	WTKYEEDKFYLEPYL	acetylation	[1, 2]
96	FYLEPYLKEVIRERK	acetylation	[2]
110	KEREEWAKK******	acetylation	[2]

Reference

 [1] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This component is involved in redox-linked proton pumping (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 12 12 N6-acetyllysine.
 MOD_RES 88 88 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 111 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0005750; C:mitochondrial respiratory chain complex III; IEA:InterPro.
 GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:InterPro. 

Interpro

 IPR003197; QCR7. 

Pfam

 PF02271; UCR_14kD 

SMART

  

PROSITE

  

PRINTS