UniProt Accession

 YBEY_ECOLI; P0A898; P77385 

Genbank Protein ID

 U82598; U00096; AP009048 

Genbank Nucleotide ID

 AAB40861.1; AAC73760.1; BAA35314.1 

Protein Name

 Endoribonuclease YbeY 

Protein Synonyms/Alias

  

Gene Name

 ybeY 

Gene Synonyms/Alias

 b0659; JW0656 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
95	ICRQVVEKEAQEQGK	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. Acts together with the RNase R to eliminate defective 70S ribosomes, but not properly matured 70S ribosomes or individual subunits, by a process mediated specifically by the 30S ribosomal subunit. Involved in the processing of 16S, 23S and 5S rRNAs, with a particularly strong effect on maturation at both the 5'-and 3'-ends of 16S rRNA as well as maturation of the 5'-end of 23S and 5S rRNAs. 

Sequence Annotation

 METAL 114 114 Zinc; catalytic (Probable).
 METAL 118 118 Zinc; catalytic (Probable).
 METAL 124 124 Zinc; catalytic (Probable).  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Endonuclease; Hydrolase; Metal-binding; Nuclease; Reference proteome; Ribosome biogenesis; rRNA processing; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 155 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004521; F:endoribonuclease activity; IEA:HAMAP.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0016151; F:nickel cation binding; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IEA:HAMAP.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC.
 GO:0009408; P:response to heat; IMP:EcoCyc.
 GO:0042274; P:ribosomal small subunit biogenesis; IMP:EcoCyc.
 GO:0006364; P:rRNA processing; IMP:UniProtKB.
 GO:0006412; P:translation; IMP:EcoCyc. 

Interpro

 IPR023091; MetalPrtase_cat_dom_prd.
 IPR002036; YbeY.
 IPR020549; YbeY_CS. 

Pfam

 PF02130; UPF0054 

SMART

  

PROSITE

 PS01306; UPF0054 

PRINTS